CAJ | 학술논문

目的从巴西巴豆属药用植物的一新变种复制Muel的叶中分离生物碱成分.方法应用硅胶柱层析法分离和纯化,波谱分析与已知化合物的波谱和理化性质比较得以确定化合物结构.结果分离得到12个生物碱,其中4个为新生物碱,命名为hemiargine A(1),B(5),C(6)和D(7);8个已知生物碱为isocorydine(2),corydine(3),noreorydine(4),salutari-dine(8),glaucine(9),tetrahydropalmatrubine(10),xylopinoine(11)和norlaudanosine(12).结论获得4种新化合物,除生物碱(8),其余生物碱均为首次从该属植物中获得.
목적종파서파두속약용식물적일신변충복제Muel적협중분리생물감성분.방법응용규효주층석법분리화순화,파보분석여이지화합물적파보화이화성질비교득이학정화합물결구.결과분리득도12개생물감,기중4개위신생물감,명명위hemiargine A(1),B(5),C(6)화D(7);8개이지생물감위isocorydine(2),corydine(3),noreorydine(4),salutari-dine(8),glaucine(9),tetrahydropalmatrubine(10),xylopinoine(11)화norlaudanosine(12).결론획득4충신화합물,제생물감(8),기여생물감균위수차종해속식물중획득.
Aim Investigation of alkaloids from the leaves of Brazilian medicinal plant Croton hemiargyerius var.gymnodiscus. Methods Silica gel column chromatography was used repeatedly for the isolation and purification, and their structures were identified by extensive spectroscopy and comparison of the chemical and physical data with those of authentic samples reported in literature. Results Twelve alkaloids were isolated and their structures were identified. Conclusion Four new alkaloids named hemiargines A (1), B (5), C (6) and D (7), together with eight known alkaloids namely isocorydine (2), corydine (3), norcorydine (4), salutaridine (8), glaucine (9), tetrahydropalmatrubine (10), xylopinoine (11), and norlaudanosine (12) were isolated.