CAJ | 학술논문

从西藏胡黄连中分离和鉴定了4个化合物, 其中化合物1是新化合物, 命名为西藏胡黄连酚苷E(Scrophenoside E), 结构为(2-甲氧基-4-乙酰基)苯酚-3-β-D-吡喃葡萄糖基-6-O-(4-β-D-吡喃葡萄糖基)香草酰基-β-D-吡喃葡萄糖苷.
종서장호황련중분리화감정료4개화합물, 기중화합물1시신화합물, 명명위서장호황련분감E(Scrophenoside E), 결구위(2-갑양기-4-을선기)분분-3-β-D-필남포도당기-6-O-(4-β-D-필남포도당기)향초선기-β-D-필남포도당감.
Xizang Huhuanglian, the roots of Picrorhiza scrophulariiflora Pennell, is a traditional Chinese Medicine used to treat damp-heat dysentery, jaundice, indigestion, common fever, acute viral hepatitis, and steaming of bone. The scholars of domestic and foreign have studied on the pharmacological effects of the plant, and found that the plant will be one of the most effective preparation in protecting the liver. This plant is rich in terpenoids, iridoid glycosides, phenolic glycosides and phenylethanoid glycosides. These compounds of the plant were isolated via silica gel column, D101 macroporous column, Sephadex LH-20 column, ODS column chromatography and HPLC. The structures of these compounds were identified by spectroscopic methods(NMR, IR, UV and MS) and chemical methods. Four compounds from this plant were obtained. Their names are Scrophenoside E(1) [(6-(4-acetyl-2-methoxyphenoxy)-3,5-dihydroxy-4-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yl)methyl-3-methoxy-4-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)benzoate], Coniferin(2), Arbutin(3) and Androsin(4). Scrophenoside E is a new compound. Coniferin, Arbutin and Androsin are three known compounds.