CAJ | 학술논문

目的探讨姑息性胃大部切除加术中植入125I放射性粒子治疗胃癌浸润胰腺患者的可行性和安全性.方法对术中发现胃癌向胰腺浸润,并难以彻底切除者,在姑息性切除胃癌的同时,在胰腺残留癌组织内植入125I放射性粒子.结果自2004年12月至2009年6月用该方法治疗晚期胃癌15例,男9例,女6例;年龄41～78岁(中位年龄64岁);其中胃癌向胰腺头部浸润5例,向胰腺颈、体部浸润10例.术后发生胰瘘1例,继发性出血1例,经随访,CR 5例(33.3%),PR 9例(60%),NC 1例(6.7%),无PD病例.结论对晚期胃癌浸润胰腺患者采用姑息性胃大部切除加术中植入125I粒子的方法是安全可行的,不会增加术后并发症的发生率,具有较好的临床应用价值.
목적 탐토고식성위대부절제가술중식입125I방사성입자치료위암침윤이선환자적가행성화안전성.방법 대술중발현위암향이선침윤,병난이철저절제자,재고식성절제위암적동시,재이선잔류암조직내식입125I방사성입자.결과 자2004년12월지2009년6월용해방법치료만기위암15례,남9례,녀6례;년령41～78세(중위년령64세);기중위암향이선두부침윤5례,향이선경、체부침윤10례.술후발생이루1례,계발성출혈1례,경수방,CR 5례(33.3%),PR 9례(60%),NC 1례(6.7%),무PD병례.결론 대만기위암침윤이선환자채용고식성위대부절제가술중식입125I입자적방법시안전가행적,불회증가술후병발증적발생솔,구유교호적림상응용개치.
Objective To observe the feasibility of 125I intra-operative implantation plus palliative resection of gastric carcinoma for treatment of advanced gastric cancer infiltrating pancreas. Methods 125 I was implanted intraoperatively into the residual pancreatic cancer tissues after gastric carcinoma was palliatively removed. Results From Feb. 2005 to Jun. 2009, 15 cases (9 male, 6 female) advanced gastric cancer patients were treated with 125 I intra-operative implantation. The patients' ages ranged from 41 to 78 years, with the median age of 64 years old. There were 10 cases of gastric cancer infiltrating the neck or body of pancreas and 5 cases infiltrating pancreatic head. No severe post-operative complications were recorded. The follow-up showed that there were 5 cases of CR (33.3%), 9 cases of PR (60%), 1 case of NC (6.7%) and no PD patients were found. Conclusion 125I intra-operative implantation plus palliative gastric resection is feasible and effective for patients of advanced gastric cancer infiltrating the pancreas.