CAJ | 학술논문

目的通过对子宫颈癌调强放疗各种布野方案的比较,探讨符合临床要求的最佳照射方案.方法对10例子宫颈癌患者采用调强治疗方案,处方剂量为46 Gy,分次量为2 Gy.每位患者做6个不同的治疗计划,分别为5野、7野、9野均分照射,初始入射角度选用0°和180°.分别计算比较靶区的覆盖度、均匀性、适形度各项指标.结果 7野和9野的靶区适形度基本一致,7野的均匀性最好,5野靶区覆盖度也能达到要求,但适形度和均匀度都次于7、9野;9野IMRT计划与5野IMRT计划相比没有减少正常组织的受照剂量,但增加了子野数和照射的总跳数,延长了治疗时间.结论在子宫颈癌的调强放疗中,综合考虑各种物理和生物因素,建议在设计照射野时尽量选择7野照射.
목적 통과대자궁경암조강방료각충포야방안적비교,탐토부합림상요구적최가조사방안.방법 대10례자궁경암환자채용조강치료방안,처방제량위46 Gy,분차량위2 Gy.매위환자주6개불동적치료계화,분별위5야、7야、9야균분조사,초시입사각도선용0°화180°.분별계산비교파구적복개도、균균성、괄형도각항지표.결과 7야화9야적파구괄형도기본일치,7야적균균성최호,5야파구복개도야능체도요구,단괄형도화균균도도차우7、9야;9야IMRT계화여5야IMRT계화상비몰유감소정상조직적수조제량,단증가료자야수화조사적총도수,연장료치료시간.결론 재자궁경암적조강방료중,종합고필각충물리화생물인소,건의재설계조사야시진량선택7야조사.
Objective To find the optimal beam arrangement for clinical cervical cancer treatment with intensitv modulated radiation therapy (IMRT) technique through comparison between different beam arrangements.Methods Six IMRT plans were designed for 10 patients with cervical cancer.The prescribed dose was 46 Gy,while the fractionated dose was 2 Gy,and 5,7,9 equispaced beams were applied.The initial beam angle degrees were O and 180.The terms of target coverage,target dose uniformitv.and target conformability were calculated and compared. Results The target conformabilities between 7 and 9-beam plans were identical,and dose uniformity between the tWo angles beams was the best in 7-beam D1an.The target coverage was satisfactory in 5-beam plan,but the dose uniformity and target conformability in it were inferior to those in 7 and 9-beam plans.The dose on normal tissues in 9-beam plan was not less than that in 5-beam plans,but the treatment was prolonged due to the increased segments and monitor units (MU). Conclusions Considering the physical and biological factors during the cervical cancer Ireatment with IMRT,7-beam plan would be the best choice for the beam design.