CAJ | 학술논문

目的了解肾移植术后颈内静脉留置导管细菌定植情况及耐药性的特点,为预防肾移植术后导管相关感染提供可靠的依据.方法对住院的49例肾移植受者在术后第2天、第4天进行导管腔内血培养和拔除导管时导管尖端培养,对分离菌株进行鉴定和药敏试验.结果共收集细菌培养标本113份,其中,术后第2天标本42份,术后第4天标本48份,导管尖端标本23份,培养阳性率分别为2.4%(1/42)、29.2%(14/48)和65.2%(15/23).术后第4天培养阳性率较术后第2天明显上升.培养获得的菌株以葡萄球菌为主.结论随着使用时间的延长,导管内细菌定植几率增加.临床上需严格无菌操作技术,根据药敏试验结果应用抗生素封管,减少导管相关感染.
목적 료해신이식술후경내정맥류치도관세균정식정황급내약성적특점,위예방신이식술후도관상관감염제공가고적의거.방법 대주원적49례신이식수자재술후제2천、제4천진행도관강내혈배양화발제도관시도관첨단배양,대분리균주진행감정화약민시험.결과공수집세균배양표본113빈,기중,술후제2천표본42빈,술후제4천표본48빈,도관첨단표본23빈,배양양성솔분별위2.4%(1/42)、29.2%(14/48)화65.2%(15/23).술후제4천배양양성솔교술후제2천명현상승.배양획득적균주이포도구균위주.결론 수착사용시간적연장,도관내세균정식궤솔증가.림상상수엄격무균조작기술,근거약민시험결과응용항생소봉관,감소도관상관감염.
Objective To analyze the characteristics of bacterial colonization and drug resistance in catheter insertion through internal jugular vein,and provide a reliable basis for the prevention of catheter-related infection after kidney transplantation.Methods The strains of bacteria isolated from catheter cavity blood culture at the second and fourth day after Results A total of 113 samples were collected,including 42 samples of catheter cavity blood culture at the second day after renal transplantation,48 samples at the fourth day after renal transplantation,and 23 samples of catheter tip culture.The positive rates were 2.4%(1/42),29.2%(14/48)and 65.2%(15/23),respectively.The positive rate at the fourth day after renal transplantation was significantly higher than that of the second day.The top three isolated bacteria were Staphylococcus epidermidis,Staphylococcus simulans and Corynebacterium.Conclusion The incidence of bacterial colonization in internal jugular vein indwelling catheter increased as time prolonging.It is suggested to strictly execute aseptic techniques and use antibiotics according to drug resistance analysis to reduce the catheter-related infection in kidney transplant patients.