中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
11期
827-830
,共4页
张晓峰%李龙标%丁洁%沈博渊%马晓玲
張曉峰%李龍標%丁潔%瀋博淵%馬曉玲
장효봉%리룡표%정길%침박연%마효령
准分子激光上皮下角膜磨镶术%角膜厚度%圆锥角膜
準分子激光上皮下角膜磨鑲術%角膜厚度%圓錐角膜
준분자격광상피하각막마양술%각막후도%원추각막
Laser subepithelial keratomileusis%Corneal thickness%Keratoconus
目的 评价准分子激光上皮下角膜磨镶术(LASEK)矫治薄角膜(中央角膜厚度＜ 500μm)中低度近视的远期效果和安全性.方法 回顾分析LASEK矫治中低度近视术后5～7年,对比术前薄角膜者与正常角膜厚度者的屈光度、视力、对比敏感度、眩光对比敏感度、角膜内皮细胞、角膜地形图.结果 薄角膜组27例52眼,正常角膜厚度组31例62眼.两组术后随访均未见圆锥角膜病例.术后矫正视力均≥1.0.裸眼视力:薄角膜组≥1.0者49眼(94.23％),＜1.0者3眼；正常角膜组≥1.0者58眼(93.55％),＜1.0者4眼(x2=0.0228,P＞0.05).角膜Haze:薄角膜组0级49眼(94.23％),0.5级3眼；正常角膜组0级60眼(96.77％),0.5级2眼(x2=0.4416,P＞0.05).角膜内皮细胞形态两组均多为六角形,形态较一致,细胞边缘整齐；平均角膜内皮细胞密度:薄角膜组(2330±294) /mm2,正常角膜组(2413±320)/mm2(t=1.4310,P＞0.05)；平均角膜内皮细胞面积:薄角膜(420±78) μm2,正常角膜组(447±92)μm2(t=1.6875,P＞0.05).两组术后各空间频率对比敏感度、眩光对比敏感度均差无差别(P＞0.05).结论 LASEK矫治薄角膜中低度近视安全,效果稳定,未见圆锥角膜并发症.
目的 評價準分子激光上皮下角膜磨鑲術(LASEK)矯治薄角膜(中央角膜厚度＜ 500μm)中低度近視的遠期效果和安全性.方法 迴顧分析LASEK矯治中低度近視術後5～7年,對比術前薄角膜者與正常角膜厚度者的屈光度、視力、對比敏感度、眩光對比敏感度、角膜內皮細胞、角膜地形圖.結果 薄角膜組27例52眼,正常角膜厚度組31例62眼.兩組術後隨訪均未見圓錐角膜病例.術後矯正視力均≥1.0.裸眼視力:薄角膜組≥1.0者49眼(94.23％),＜1.0者3眼；正常角膜組≥1.0者58眼(93.55％),＜1.0者4眼(x2=0.0228,P＞0.05).角膜Haze:薄角膜組0級49眼(94.23％),0.5級3眼；正常角膜組0級60眼(96.77％),0.5級2眼(x2=0.4416,P＞0.05).角膜內皮細胞形態兩組均多為六角形,形態較一緻,細胞邊緣整齊；平均角膜內皮細胞密度:薄角膜組(2330±294) /mm2,正常角膜組(2413±320)/mm2(t=1.4310,P＞0.05)；平均角膜內皮細胞麵積:薄角膜(420±78) μm2,正常角膜組(447±92)μm2(t=1.6875,P＞0.05).兩組術後各空間頻率對比敏感度、眩光對比敏感度均差無差彆(P＞0.05).結論 LASEK矯治薄角膜中低度近視安全,效果穩定,未見圓錐角膜併髮癥.
목적 평개준분자격광상피하각막마양술(LASEK)교치박각막(중앙각막후도＜ 500μm)중저도근시적원기효과화안전성.방법 회고분석LASEK교치중저도근시술후5～7년,대비술전박각막자여정상각막후도자적굴광도、시력、대비민감도、현광대비민감도、각막내피세포、각막지형도.결과 박각막조27례52안,정상각막후도조31례62안.량조술후수방균미견원추각막병례.술후교정시력균≥1.0.라안시력:박각막조≥1.0자49안(94.23％),＜1.0자3안；정상각막조≥1.0자58안(93.55％),＜1.0자4안(x2=0.0228,P＞0.05).각막Haze:박각막조0급49안(94.23％),0.5급3안；정상각막조0급60안(96.77％),0.5급2안(x2=0.4416,P＞0.05).각막내피세포형태량조균다위륙각형,형태교일치,세포변연정제；평균각막내피세포밀도:박각막조(2330±294) /mm2,정상각막조(2413±320)/mm2(t=1.4310,P＞0.05)；평균각막내피세포면적:박각막(420±78) μm2,정상각막조(447±92)μm2(t=1.6875,P＞0.05).량조술후각공간빈솔대비민감도、현광대비민감도균차무차별(P＞0.05).결론 LASEK교치박각막중저도근시안전,효과은정,미견원추각막병발증.
Objective To evaluate the long term effect and safety of laser subepithelial keratomileusis( LASEK)for the treatment of low to moderate myopia with thin cornea( central corneal thickness ＜ 500 μm) Methods To analyze patients with low to moderate myopia in 5 -7 years after LASEK,and compare the refraction,visual acuity,contrast sensitivity,glare contrast sensitivity,corneal endothelium and corneal topography between pateints with thin cornea and normal thickness cornea.Results Thin cornea group had 27 cases (52 eyes).Normal thickness cornea group had 31 cases (62 eyes).No keratoconus had been observed during the follow-up period in the two groups.The corrected visual acuity of both groups were ≥1.0 ;In the thin cornea group,49 eyes' uncorrected visued acuity were ≥ 1.0,and 3 eyes were ＜ 1.0.In the normal cornea group,58 eyes' uncorreeted visued acuity were ≥ 1.0,and 4 eyes were ＜ 1.0 (x2 ＝ 0.0228,P ＞ 0.05).In the thin cornea group,49 eyes had 0 degree of cornea Haze,and 3 eyes had 0.5 degrees of cornea Haze.On the other hand,in the normal thickness cornea group,60 eyes had 0 degree of cornea Haze,and 2 eyes had 0.5 degrees of cornea Haze(x2 =0.4416,P ＞ 0.05 ).The shapes of the corneal endothelium of bothgroups were quite consistent and appear to be hexagonal,and the cell edge was neat.The average endothelial cell density:(2330±294)/mm2 in the thin cornea group,and (2413 ±320)/mm2 in the normal corneal thickness group; The average endothelial cell area:(420 ± 78 )μm2 in the thin cornea group,and (447 ± 92 ) μm2 ( t =1.6875,P ＞ 0.05 ) in the normal thickness cornea group.The contrast sensitivity of two groups with or without glare condition had significant difference for every spatial frequencies (P ＞ 0.05 ).Conclusion LASEK for the treatment of low to moderate myopia with thin cornea is tested to be safe,stable and with no keratoconus.
