CAJ | 학술논문

　　目的加深对特发性腹膜后纤维化疾病的认识，提高早期诊断和治疗水平。方法分析我科收治1例特发性腹膜后纤维化导致急性肾损害患者的诊治过程，并复习近年国内外有关腹膜后纤维化的文献资料。结果本例患者以双下肢浮肿就诊。腹部彩超：双肾积水。CT腹主动脉周围及后方可见不规则软组织密度影，左侧髂动脉前移，双侧肾盂扩张积水改变，双侧输尿管中上端扩张，腹主动脉下段及髂动脉扩张。化验：肾功能：血肌酐186μmol/L，尿素氮10.89mmol/L，血沉74mm/h，γ球蛋白25.3%，α2球蛋白8%。结合影像学检查及化验确诊为：特发性腹膜后纤维化并急性肾损害。经过强的松治疗近期临床效果满意。结论特发性腹膜后纤维化发病率低，临床表现缺乏特异性，早期误诊率高，影像学检查是明确诊断的重要举措。糖皮质激素对特发性腹膜后纤维化治疗效果较好。
　　목적가심대특발성복막후섬유화질병적인식，제고조기진단화치료수평。방법분석아과수치1례특발성복막후섬유화도치급성신손해환자적진치과정，병복습근년국내외유관복막후섬유화적문헌자료。결과본례환자이쌍하지부종취진。복부채초：쌍신적수。CT복주동맥주위급후방가견불규칙연조직밀도영，좌측가동맥전이，쌍측신우확장적수개변，쌍측수뇨관중상단확장，복주동맥하단급가동맥확장。화험：신공능：혈기항186μmol/L，뇨소담10.89mmol/L，혈침74mm/h，γ구단백25.3%，α2구단백8%。결합영상학검사급화험학진위：특발성복막후섬유화병급성신손해。경과강적송치료근기림상효과만의。결론특발성복막후섬유화발병솔저，림상표현결핍특이성，조기오진솔고，영상학검사시명학진단적중요거조。당피질격소대특발성복막후섬유화치료효과교호。
Objective To investigate the early diagnosis and treatment for retroperitoneal fibrosis(RPF). Methods The processes of the diagnosis and therapy were analyzed for one patient with idiopathic retroperitoneal fibrosis(IRF).Admitted to our department and the domestic and foreign literature materials about RPF in recent years were reviewed.Results Patients withapair of lower limbs dropsy to clinic. Abdominal ultrasound results;bilateral hydronephrosis.A soft—tissue mass surrounding the abdominal aorta in retroperitoneal,left arterial iliac was antedisplacement,Bilateral renal pelvis Expansion The upper of Bilateral urethral expansion,Expansion of Abdominal aorta under paragraph and Iliac artery was showed by CT. SCR:1 86μmol/L, BUN:10. 89mmol/L, ESR:7 m m/h,γ-Globulin25.3%,α2Globulin8%. According to the imaging examination and laboratory diagnosis;The idiopathic retroperitoneal fibrosis and Acute renal damage.After Prednisone therapy has Satisfactory clinical effect.Conclusion RPF isarare disease and often hasamisdiagnosis and symptoms was no-specific in the early phase.Analysis of imaging conduce to refine the diagnostic process . Corticos teroidhasa good effectiveness on the treatment of most cases with RPF.