CAJ | 학술논문

目的探讨儿童甲型H1N1流感并急性坏死性脑病(ANE)的CT及MRI表现.方法分析经过临床实验室检查确诊的3例儿童甲型H1N1流感并ANE患者的颅脑CT及MRI影像表现.各患儿住院期间均因昏迷而行颅脑CT及MRI扫描.结果 3例儿童甲型H1N1流感并ANE的颅脑CT及MRI影像表现为多灶性、部分对称性脑部损害,以累及双侧丘脑为共同点；双侧大脑半球额、颞、顶、枕叶灰白质,海马区、豆状核、外囊、脑干及双侧小脑半球灰白质多灶性、部分对称性脑部损害,并以灰质损害为主；不同程度脑肿胀.病变区CT表现为密度减低；MRI呈长T1、长T2信号,FLAIR系列呈较高信号.结论儿童甲型H1N1流感并ANE影像表现为脑内多灶性、部分对称性脑部损害及脑水肿,影像学以累及双侧丘脑为特征,病情严重,病死率极高,临床应予以高度重视.
목적 탐토인동갑형H1N1류감병급성배사성뇌병(ANE)적CT급MRI표현.방법 분석경과림상실험실검사학진적3례인동갑형H1N1류감병ANE환자적로뇌CT급MRI영상표현.각환인주원기간균인혼미이행로뇌CT급MRI소묘.결과 3례인동갑형H1N1류감병ANE적로뇌CT급MRI영상표현위다조성、부분대칭성뇌부손해,이루급쌍측구뇌위공동점；쌍측대뇌반구액、섭、정、침협회백질,해마구、두상핵、외낭、뇌간급쌍측소뇌반구회백질다조성、부분대칭성뇌부손해,병이회질손해위주；불동정도뇌종창.병변구CT표현위밀도감저；MRI정장T1、장T2신호,FLAIR계렬정교고신호.결론 인동갑형H1N1류감병ANE영상표현위뇌내다조성、부분대칭성뇌부손해급뇌수종,영상학이루급쌍측구뇌위특정,병정엄중,병사솔겁고,림상응여이고도중시.
Objective To evaluate the imaging features of acute necrotizing encephalopathy caused by children A H1N1 influenza.Methods CT and MRI brain imaging data of three children acute necrotizing encephalopathy caused by A H1N1 influenza virus and proved by clinical and laboratory investigation were analyzed.All the three children got CT and MRI scan because of coma while in hospital.Results All cases represented multifocal damage,and some were symmetrical.Bilateral thalamencephalons were involved in the all cases.Bilateral grey and white matters of frontal lobe,temporal lobe,parietal lobe and occipital lobe,and hippocampi,putamina,external capsule,brain stem,bilateral cerebellum,could be seen multifocal damage,and some were symmetrical.All the cases showed brain swelling in varying degrees.These region presented low density in CT,hypointensity on T1 weighted series and hyperintensity on T2 weighted series and FLAIR series in MRI.Conclusion The imaging features of acute necrotizing encephalopathy caused by children A H1N1 influenza represented multifocal and symmetrical damage and brain swelling.It may be characteristic that bilateral thalamencephaloas were involved.The patient was serious,and fatality rate was high.So we should pay much attention to acute necrotizing encephalopathy caused by children A H1 N1 influenza.