CAJ | 학술논문

目的探讨非抽搐性癫痫持续状态(NCSE)患者的临床表现及持续脑电监测的脑电图(EEG)特征.方法对自2008年11月至2009年12月北京大学人民医院急诊科收治的5例NCSE患者行持续EEG监测检查,观察其EEG特征及临床表现.结果 5例均出现发作性意识障碍,其中4例出现烦躁、易怒或躁狂,3例表现出精神运动迟滞和遗忘,2例出现言语自动症和失认,1例出现定向障碍.所有患者的EEG均出现广泛性但一侧明显的异常放电.静脉注射地两泮后,3例患者临床症状迅速改善.结论 NCSE并非罕见,持续EEG监测能查出本病,早期诊断,及时治疗可改善患者预后,临床应注意与其他引起意识紊乱的疾病相鉴别.
목적 탐토비추휵성전간지속상태(NCSE)환자적림상표현급지속뇌전감측적뇌전도(EEG)특정.방법 대자2008년11월지2009년12월북경대학인민의원급진과수치적5례NCSE환자행지속EEG감측검사,관찰기EEG특정급림상표현.결과 5례균출현발작성의식장애,기중4례출현번조、역노혹조광,3례표현출정신운동지체화유망,2례출현언어자동증화실인,1례출현정향장애.소유환자적EEG균출현엄범성단일측명현적이상방전.정맥주사지량반후,3례환자림상증상신속개선.결론 NCSE병비한견,지속EEG감측능사출본병,조기진단,급시치료가개선환자예후,림상응주의여기타인기의식문란적질병상감별.
Objective To describe the clinical and electroencephalographic features as well as the possible etiology and treatment of patients with non-convulsive status epilepticus (NCSE). Methods We identified 5 adult patients with NCSE from the epilepsy database of the comprehensive epilepsy. Continuous electroencephalographic (EEG) monitoring was analyzed and chart review was performed to analyze their clinical and electroencephalographic features. Results The patients ranged from 19 to 66 years old. All of the 5 patients showed impaired consciousness: 4 demonstrated agitation and paranoia; 3 had both psychomotor retardation and amnesia; 2 developed verbal automatisms and agnosia; and 1 had disorientation. All the patients had associated generalized discharges but lateralized dominant. Three patients showed clinical improvement following administration of benzodiazepines. Conclusion The NCSE is not a rare case and continuous EEG monitoring can help the diagnosis. Prompt recognition and treatment may be necessary in improving the neurological outcome, and attention should be paid to the identification with other diseases that cause impairment of conscience.