中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2011年
1期
56-58
,共3页
颅脑损伤%意识障碍%预后%定量脑电图
顱腦損傷%意識障礙%預後%定量腦電圖
로뇌손상%의식장애%예후%정량뇌전도
Craniocerebral trauma%Consciousness disorders%Prognosis%Quantitative electroencephalography
目的 探讨定量脑电图在重型颅脑创伤后长期意识障碍患者预后中的应用.方法 收集我院重型颅脑创伤意识障碍超过2周的患者41例,分成清醒组(19例)和未清醒组(22例),均于入院后2周行脑电图检查获取原始脑电图资料,采样后借助计算机软件行快速傅里叶转换进行功率谱分析,功率谱按频率分为δ(1.0~4.0 Hz)、θ(4.1~8.0 Hz)、α1(8.1~10.0 Hz)、α2(10.1~13 Hz)、β1(13.1~17.5 Hz)、β2(17.6~35.0 Hz)6个频带,计算出各个频带的绝对功率值及δ+θ/α+β值并以δ+θ/α+β值作为患者顸后评判指标,进行两个病例组之间的关系研究,以颅脑创伤后6个月患者是否清醒为标准.结果 清醒组的6+θ/α+β值((-x)±s)为5.432±3.277,未清醒组的δ+θ/α+β值((-x)±s)为8.724±5.641.清醒组和末清醒组行两独立样本t检验,两组病例间差异有统计学意义,t=2.237(P=0.030).清醒患者的GCS评分和δ+θ/α+β值行Pearson相关分析,得出r=-0.622,P=0.004,两者呈负相关.结论 定量脑电图作为一种廉价、客观、快速的脑功能评价手段,可准确地反映颅脑创伤程度和预后.
目的 探討定量腦電圖在重型顱腦創傷後長期意識障礙患者預後中的應用.方法 收集我院重型顱腦創傷意識障礙超過2週的患者41例,分成清醒組(19例)和未清醒組(22例),均于入院後2週行腦電圖檢查穫取原始腦電圖資料,採樣後藉助計算機軟件行快速傅裏葉轉換進行功率譜分析,功率譜按頻率分為δ(1.0~4.0 Hz)、θ(4.1~8.0 Hz)、α1(8.1~10.0 Hz)、α2(10.1~13 Hz)、β1(13.1~17.5 Hz)、β2(17.6~35.0 Hz)6箇頻帶,計算齣各箇頻帶的絕對功率值及δ+θ/α+β值併以δ+θ/α+β值作為患者頇後評判指標,進行兩箇病例組之間的關繫研究,以顱腦創傷後6箇月患者是否清醒為標準.結果 清醒組的6+θ/α+β值((-x)±s)為5.432±3.277,未清醒組的δ+θ/α+β值((-x)±s)為8.724±5.641.清醒組和末清醒組行兩獨立樣本t檢驗,兩組病例間差異有統計學意義,t=2.237(P=0.030).清醒患者的GCS評分和δ+θ/α+β值行Pearson相關分析,得齣r=-0.622,P=0.004,兩者呈負相關.結論 定量腦電圖作為一種廉價、客觀、快速的腦功能評價手段,可準確地反映顱腦創傷程度和預後.
목적 탐토정량뇌전도재중형로뇌창상후장기의식장애환자예후중적응용.방법 수집아원중형로뇌창상의식장애초과2주적환자41례,분성청성조(19례)화미청성조(22례),균우입원후2주행뇌전도검사획취원시뇌전도자료,채양후차조계산궤연건행쾌속부리협전환진행공솔보분석,공솔보안빈솔분위δ(1.0~4.0 Hz)、θ(4.1~8.0 Hz)、α1(8.1~10.0 Hz)、α2(10.1~13 Hz)、β1(13.1~17.5 Hz)、β2(17.6~35.0 Hz)6개빈대,계산출각개빈대적절대공솔치급δ+θ/α+β치병이δ+θ/α+β치작위환자한후평판지표,진행량개병례조지간적관계연구,이로뇌창상후6개월환자시부청성위표준.결과 청성조적6+θ/α+β치((-x)±s)위5.432±3.277,미청성조적δ+θ/α+β치((-x)±s)위8.724±5.641.청성조화말청성조행량독립양본t검험,량조병례간차이유통계학의의,t=2.237(P=0.030).청성환자적GCS평분화δ+θ/α+β치행Pearson상관분석,득출r=-0.622,P=0.004,량자정부상관.결론 정량뇌전도작위일충렴개、객관、쾌속적뇌공능평개수단,가준학지반영로뇌창상정도화예후.
Objective To explore the quantitative electroencephalography in unconscious patients after severe traumatic brain injury (TBI) to predict awakening.Method All cases were divided into two groups( the awake group 19 cases and the unfavourable prognosis group 22 cases).Two weeks after admission the original EEGs were preformed in 41 patients suffering from severe TBI with duration of disturbance of unconsciousness ≥2 weeks.The sampled data did make fast Fourier transform to obtain the power spectrum analysis with the computer software.The power spectrum was divided into 6 bandwidth by frequency: δ( 1.0~4.0 Hz)、θ(4.1 ~8.0 Hz) 、α1(8.1 ~10.0 Hz) 、α2(10.1 ~13 Hz) 、β1 (13.1 ~17.5 Hz) 、β2(17.6 ~35.0 Hz).Calculate the absolute power value in each band and δ + θ/β + β value and research the correlation of the both group.The awakening after the sixth months from injury was used as the criterion.Results The score of δ + θ/α + β was 5.432 ± 3.277 in the awake group,yet in the unfavourable prognosis group was 8.724 ± 5.641.Using the two independent sample t test, both groups had significant difference, t =2.237 ( P = 0.030 ).Using Pearson correlation analysis, r = - 0.622, P = 0.004, both Glasgow coma score and δ + θ/α + β value had negative correlation.Conclusions As an inexpensive,objective and rapid means of the evaluation of brain function,the QEEG can accurately reflect the degree of brain dysfunction and assess the prognosis of patients.