CAJ | 학술논문

目的评价经尿道前列腺切除术(TURP)在前列腺癌早期诊断中的作用.方法采用TURP方法对16例血清前列腺特异抗原(PSA)轻度升高(平均11.7 ng/ml),直肠指诊和前列腺穿刺活检阴性,但PSA持续升高或者合并有明显下尿路症状,或者PSA升高却不宜活检的可疑前列腺癌病例行TURP.6例通过病理学诊断确诊前列腺癌.其中3例又行双侧睾丸切除术加间断抗雄激素药物治疗,2例行药物去势加抗雄激素药物治疗,1例在新辅助内分泌治疗后行根治性前列腺切除术.结果对6例经TURP诊断为前列腺癌的患者随访3个月～2年,全部生存.TURP使2例前列腺癌合并下尿路症状患者的症状得到缓解.结论 TURP对部分前列腺癌有早期诊断作用,同时可以缓解合并的下尿路症状.
목적 평개경뇨도전렬선절제술(TURP)재전렬선암조기진단중적작용.방법 채용TURP방법대16례혈청전렬선특이항원(PSA)경도승고(평균11.7 ng/ml),직장지진화전렬선천자활검음성,단PSA지속승고혹자합병유명현하뇨로증상,혹자PSA승고각불의활검적가의전렬선암병례행TURP.6례통과병이학진단학진전렬선암.기중3례우행쌍측고환절제술가간단항웅격소약물치료,2례행약물거세가항웅격소약물치료,1례재신보조내분비치료후행근치성전렬선절제술.결과 대6례경TURP진단위전렬선암적환자수방3개월～2년,전부생존.TURP사2례전렬선암합병하뇨로증상환자적증상득도완해.결론 TURP대부분전렬선암유조기진단작용,동시가이완해합병적하뇨로증상.
Objective To evaluate the role of transurethral resection of the prostate(TURP)in early diagnosis of prostate carcinoma.Methods TURP were perforhaed on 16 suspected patients with prostate carcinoma,based on their mean serum PSA level(11.7 ng/ml),negative results of anal touch and needle system biopsies,or with lower urinary tract symptoms,or those biopsy was not fit.6 cases were diagnosed prostate carcinoma by pathology.3 cases underwent double orchieetomy and treated with anti-androgen drugs.2 cases were emasculated by medicines and treated with anti-androgen drugs.1 case underwent radical prostatectomy after neoadjuvant hormonal therapy.Results 6 cases(37.5%)diagnosed prostate carcinoma by pathology were followed up for 3 months to 2 years and were all alive.Lower urinary tract symptoms were relived in 2 patients who underwent TURP. Conclusion TURP play a important role in early diagnosis of prostate carcinoma in certain circumstances.The symptoms could be relieved by TURP in patients with lower urinary tract symptoms.