中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2011年
1期
52-55
,共4页
徐吉%魏璐%俞素勤%吴颖%樊莹
徐吉%魏璐%俞素勤%吳穎%樊瑩
서길%위로%유소근%오영%번형
近视,退行性%黄斑%视野
近視,退行性%黃斑%視野
근시,퇴행성%황반%시야
Myopia,degenerative%Macula lutea%Visual field
目的 观察病理性近视患者黄斑功能的微视野检查表现.方法 回顾分析90例病理性近视患者142只眼的临床资料.所有患者均详细询问病史,并行最佳矫正视力(BCVA)、屈光度、眼轴、荧光素眼底血管造影(FFA)、间接检眼镜和黄斑部光相干断层扫描(OCT)检查.根据检查结果 将患者分为无黄斑病理改变和黄斑病理改变组,分别为20例24只眼、70例118只眼.采用MP-1微视野计对两组患者行眼底成像和黄斑部微视野检查,记录受检眼黄斑10°范围内视网膜平均光敏感度(MS)、固视稳定性、2°和4°固视率及固视点位置.结果 无黄斑病理改变组和黄斑病理改变组MS值分别为(16.39±2.12)、(10.80±4.53)dB,二者比较,差异有统计学意义(F=15.044,t=-9.314;P=0.000).无黄斑病理改变组24只眼中,固视稳定19只眼,占79.2%;相对不稳定5只眼,占20.8%.黄斑病理改变组118只眼中,固视稳定45只眼,占38.1%;相对不稳定52只眼,占44.1%;不稳定21只眼,占17.8%.两组固视稳定率比较,差异有统计学意义(χ2=13.56,P=0.000).两组2°和4°固视率比较,差异均有统计学意义(F=5.773,13.230;t=-4.110,-5.465;P值均=0.000).无黄斑病理改变组24只眼中,中心固视23只眼,占95.8%;弱中心固视1只眼,占4.2%.黄斑病理改变组118只眼中,中心固视81只眼,占68.6%;弱中心固视16只眼,占13.6%;旁中心固视21只眼,占17.8%.两组中心固视率比较,差异有统计学意义(F=9.618,t=-5.773;P=0.000).结论 病理性近视有黄斑病理改变者较无黄斑病理改变者MS、固视稳定性下降,并有旁中心固视点形成.
目的 觀察病理性近視患者黃斑功能的微視野檢查錶現.方法 迴顧分析90例病理性近視患者142隻眼的臨床資料.所有患者均詳細詢問病史,併行最佳矯正視力(BCVA)、屈光度、眼軸、熒光素眼底血管造影(FFA)、間接檢眼鏡和黃斑部光相榦斷層掃描(OCT)檢查.根據檢查結果 將患者分為無黃斑病理改變和黃斑病理改變組,分彆為20例24隻眼、70例118隻眼.採用MP-1微視野計對兩組患者行眼底成像和黃斑部微視野檢查,記錄受檢眼黃斑10°範圍內視網膜平均光敏感度(MS)、固視穩定性、2°和4°固視率及固視點位置.結果 無黃斑病理改變組和黃斑病理改變組MS值分彆為(16.39±2.12)、(10.80±4.53)dB,二者比較,差異有統計學意義(F=15.044,t=-9.314;P=0.000).無黃斑病理改變組24隻眼中,固視穩定19隻眼,佔79.2%;相對不穩定5隻眼,佔20.8%.黃斑病理改變組118隻眼中,固視穩定45隻眼,佔38.1%;相對不穩定52隻眼,佔44.1%;不穩定21隻眼,佔17.8%.兩組固視穩定率比較,差異有統計學意義(χ2=13.56,P=0.000).兩組2°和4°固視率比較,差異均有統計學意義(F=5.773,13.230;t=-4.110,-5.465;P值均=0.000).無黃斑病理改變組24隻眼中,中心固視23隻眼,佔95.8%;弱中心固視1隻眼,佔4.2%.黃斑病理改變組118隻眼中,中心固視81隻眼,佔68.6%;弱中心固視16隻眼,佔13.6%;徬中心固視21隻眼,佔17.8%.兩組中心固視率比較,差異有統計學意義(F=9.618,t=-5.773;P=0.000).結論 病理性近視有黃斑病理改變者較無黃斑病理改變者MS、固視穩定性下降,併有徬中心固視點形成.
목적 관찰병이성근시환자황반공능적미시야검사표현.방법 회고분석90례병이성근시환자142지안적림상자료.소유환자균상세순문병사,병행최가교정시력(BCVA)、굴광도、안축、형광소안저혈관조영(FFA)、간접검안경화황반부광상간단층소묘(OCT)검사.근거검사결과 장환자분위무황반병리개변화황반병리개변조,분별위20례24지안、70례118지안.채용MP-1미시야계대량조환자행안저성상화황반부미시야검사,기록수검안황반10°범위내시망막평균광민감도(MS)、고시은정성、2°화4°고시솔급고시점위치.결과 무황반병리개변조화황반병리개변조MS치분별위(16.39±2.12)、(10.80±4.53)dB,이자비교,차이유통계학의의(F=15.044,t=-9.314;P=0.000).무황반병리개변조24지안중,고시은정19지안,점79.2%;상대불은정5지안,점20.8%.황반병리개변조118지안중,고시은정45지안,점38.1%;상대불은정52지안,점44.1%;불은정21지안,점17.8%.량조고시은정솔비교,차이유통계학의의(χ2=13.56,P=0.000).량조2°화4°고시솔비교,차이균유통계학의의(F=5.773,13.230;t=-4.110,-5.465;P치균=0.000).무황반병리개변조24지안중,중심고시23지안,점95.8%;약중심고시1지안,점4.2%.황반병리개변조118지안중,중심고시81지안,점68.6%;약중심고시16지안,점13.6%;방중심고시21지안,점17.8%.량조중심고시솔비교,차이유통계학의의(F=9.618,t=-5.773;P=0.000).결론 병이성근시유황반병리개변자교무황반병리개변자MS、고시은정성하강,병유방중심고시점형성.
Objective To observe the microperimetry performance of macular function in pathologic myopia patients. Methods The clinical data of 90 patients (142 eyes) with pathologic myopia were retrospectively analyzed. All patients were asked in details about history, and take examinations of best corrected visual acuity (BCVA), refractive dioptre, eye axis, fluorescent fundus angiography (FFA),indirect ophthalmoscopy and optical coherence tomography (OCT). According to the test results, patients were divided into non-pathological macular group (20 patients, 24 eyes) and pathological macular group (70patients, 118 eyes). Retinal imaging and macular microperimetry were measure by MP-1 Microperimeter.The mean retinal sensitivities (MS) and fixation stability in the central 10°, fixation rate and fixation position in the central 2° and 4°were determined. Results The MS of pathological and non-pathological macular group were (16.39± 2. 12), (10. 80± 4.53) dB respectively, the difference was statistically significant (F= 15.044, t=-9.314;P= 0. 000). Among 24 eyes of non-pathological macular group,fixation was stable in 19 eyes (79.17%), relative unstable in five eyes (20. 83%);among 118 eyes of pathological macular group, fixation was stable in 45 eyes (38. 14%), relative unstable in 52 eyes (44.07%), unstable in 21 eyes (17.79%), the difference was statistically significant (χ2= 13.56, P=0. 000). The differences of 2 ° and 4 ° fixation rate between those two groups are statistically significant (F=5. 773, 13. 230;t= -4. 110, -5. 465;P= 0.000) . Among 24 eyes of non-pathological macular group, center fixation occurred in 23 eyes (95.83 % ), weak center fixation occurred in one eye (4.17 %);among 118 eyes of pathological macular group, fixation center occurred in 81 eyes (68. 64%), weak center fixation occurred in 16 eyes ( 13. 56 % ),eccentric fixation occurred in 21 eyes ( 17. 80 % ), the difference was statistically significant (F=9. 618, t= -5. 773;P=0. 000). Conclusion Pathological myopia patients with pathological macular changes have decreased retinal sensitivity, decreased fixation stability and eccentric fixation points.
