CAJ | 학술논문

目的观察复方阿嗪米特肠溶片联合马来酸曲美布汀治疗功能性消化不良的的疗效.方法 104例功能性消化不良患者采用完全随机设计方法分成2组,观察组54例,给予复方阿嗪米特肠溶片100mg,3次/d,餐后服用;马来酸曲美布汀100mg,3次/d,餐前服用.对照组50例,单用复方阿嗪米特肠溶片100mg,3&/d,餐后服用,疗程均2周.观察治疗前、后,饭后腹胀及腹部不适症状改善情况、食欲改善时间及复诊率.结果 2组腹胀症状及改善食欲方面无统计学意义,饭后腹部不适症状观察组较对照组改善明显.并能降低复诊率.治疗过程中2组均无药物不良反应出现.结论复方阿嗪米特肠溶片和马来酸曲美布汀联合应用,治疗消化不良患者疗效明显,药物不良反应少,既安全又有效.
목적 관찰복방아진미특장용편연합마래산곡미포정치료공능성소화불량적적료효.방법 104례공능성소화불량환자채용완전수궤설계방법분성2조,관찰조54례,급여복방아진미특장용편100mg,3차/d,찬후복용;마래산곡미포정100mg,3차/d,찬전복용.대조조50례,단용복방아진미특장용편100mg,3&/d,찬후복용,료정균2주.관찰치료전、후,반후복창급복부불괄증상개선정황、식욕개선시간급복진솔.결과 2조복창증상급개선식욕방면무통계학의의,반후복부불괄증상관찰조교대조조개선명현.병능강저복진솔.치료과정중2조균무약물불량반응출현.결론 복방아진미특장용편화마래산곡미포정연합응용,치료소화불량환자료효명현,약물불량반응소,기안전우유효.
Objective To observe the effect of combined compound azintamide and trimebutine on functional dyspepsia (FD). Methods One hundred and four FD patients were randomly divided into two groups.The observation group (n = 54) were given both compound azintamid and trimebutine and the control group (n =50) were only given compound azintamide. Clinical symptoms in both groups were recorded for comparison. Results There was no significant difference between two groups in abdominal fullness and improving appetites, but the combined therapy could significantly reduce the frequency of further medical consultation. There were no side effects in any patients during therapy. Conclusion Combined compound azintamide and trimebutine is an optimistic therapy in FD patients with the symptoms of upper and lower abdominal upset.