中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2009年
8期
780-783
,共4页
邢海英%高惠珍%谭秀革%范常锋%高山%孙永安%张华%钟鲜华%刘惠君%黄一宁
邢海英%高惠珍%譚秀革%範常鋒%高山%孫永安%張華%鐘鮮華%劉惠君%黃一寧
형해영%고혜진%담수혁%범상봉%고산%손영안%장화%종선화%류혜군%황일저
颅内外动脉狭窄%卒中%社区人群
顱內外動脈狹窄%卒中%社區人群
로내외동맥협착%졸중%사구인군
Intra-and extraeranial large-artery stenosis%Stroke%Community population
目的 探讨北京市远郊农村40岁以上人群颅内外动脉狭窄患病率、卒中发病风险及相关危险因素.方法 整群抽样调查北京市远郊农村40岁以上人群1337例,经颅多普勒检查发现颅内外动脉狭窄89例.在平均16.7个月时对所有人群进行电话及入户随访,调查卒中发病情况.结果 1337例调查对象颅内外动脉狭窄的患病率为6.6%.其中颅内动脉狭窄5.8%、颅外动脉狭窄0.4%、颅内外动脉同时狭窄0.4%.平均16.7个月随访期内,无颅内外动脉狭窄者的脑梗死、脑出血发病密度分别为410.6、351.9/10万人年;颅内外动脉狭窄患者的脑梗死发病密度为3303.7/10万人年,无发生脑出血者;颅内外动脉狭窄组与无颅内外动脉狭窄组之间脑梗死发病差异具有统计学意义(P=0.004).脑梗死发病危险因素的logistic回归分析显示颅内外动脉狭窄(OR=6.593,95%CI:1.712～25.390,P<0.01)、吸烟(OR=8.437,95%CI:2.327～30.598,P<0.01)是脑梗死发病的独立危险因素.结论 颅内外动脉狭窄患者的脑梗死发病密度为3303.7/10万人年,明确无脑梗死或短暂性脑缺血发作病史的颅内外动脉狭窄患者的脑梗死发病密度为2799.6/10万人年,颅内外动脉狭窄、吸烟史是脑梗死发病的独立危险因素.
目的 探討北京市遠郊農村40歲以上人群顱內外動脈狹窄患病率、卒中髮病風險及相關危險因素.方法 整群抽樣調查北京市遠郊農村40歲以上人群1337例,經顱多普勒檢查髮現顱內外動脈狹窄89例.在平均16.7箇月時對所有人群進行電話及入戶隨訪,調查卒中髮病情況.結果 1337例調查對象顱內外動脈狹窄的患病率為6.6%.其中顱內動脈狹窄5.8%、顱外動脈狹窄0.4%、顱內外動脈同時狹窄0.4%.平均16.7箇月隨訪期內,無顱內外動脈狹窄者的腦梗死、腦齣血髮病密度分彆為410.6、351.9/10萬人年;顱內外動脈狹窄患者的腦梗死髮病密度為3303.7/10萬人年,無髮生腦齣血者;顱內外動脈狹窄組與無顱內外動脈狹窄組之間腦梗死髮病差異具有統計學意義(P=0.004).腦梗死髮病危險因素的logistic迴歸分析顯示顱內外動脈狹窄(OR=6.593,95%CI:1.712～25.390,P<0.01)、吸煙(OR=8.437,95%CI:2.327～30.598,P<0.01)是腦梗死髮病的獨立危險因素.結論 顱內外動脈狹窄患者的腦梗死髮病密度為3303.7/10萬人年,明確無腦梗死或短暫性腦缺血髮作病史的顱內外動脈狹窄患者的腦梗死髮病密度為2799.6/10萬人年,顱內外動脈狹窄、吸煙史是腦梗死髮病的獨立危險因素.
목적 탐토북경시원교농촌40세이상인군로내외동맥협착환병솔、졸중발병풍험급상관위험인소.방법 정군추양조사북경시원교농촌40세이상인군1337례,경로다보륵검사발현로내외동맥협착89례.재평균16.7개월시대소유인군진행전화급입호수방,조사졸중발병정황.결과 1337례조사대상로내외동맥협착적환병솔위6.6%.기중로내동맥협착5.8%、로외동맥협착0.4%、로내외동맥동시협착0.4%.평균16.7개월수방기내,무로내외동맥협착자적뇌경사、뇌출혈발병밀도분별위410.6、351.9/10만인년;로내외동맥협착환자적뇌경사발병밀도위3303.7/10만인년,무발생뇌출혈자;로내외동맥협착조여무로내외동맥협착조지간뇌경사발병차이구유통계학의의(P=0.004).뇌경사발병위험인소적logistic회귀분석현시로내외동맥협착(OR=6.593,95%CI:1.712～25.390,P<0.01)、흡연(OR=8.437,95%CI:2.327～30.598,P<0.01)시뇌경사발병적독립위험인소.결론 로내외동맥협착환자적뇌경사발병밀도위3303.7/10만인년,명학무뇌경사혹단잠성뇌결혈발작병사적로내외동맥협착환자적뇌경사발병밀도위2799.6/10만인년,로내외동맥협착、흡연사시뇌경사발병적독립위험인소.
Objective To assess the prevalence rates of intra-and extraeranial large-artery stenosis in the rural community population and its related risk to the development of stroke.Methods The study subjects included 1337 residents in the rural community of Beijing.Transcranial Doppler Was carried our to examine the relation between intra-and extracranial large-artery stenosis and subsequent cerebrovascular events, with a meall follow-up period of 16.7 months.Results The incidence densities of cerebral infarction and cerebral hemorrhage in persons without cerebral large-artery stenosis were 410.6 and 351.9/100-thousand person-years,respectively.In the group wlth large-artery stenosis,the incidence density of cerebral infarction was 3303.7/100-thousand person-years.Data from The Fisher's Exact test showed a significant difference in the two groups (P=0.004).Cerebral large-artery stenosis(OR=6.593,95%CI:1.712-25.390)and smoking (OR=8.437,95% CI:2.327-30.598)appeared to be independent risk factors to cerebral infarction.Conclusion Cerebral large-artery stenosis and smoking were independent risk factors to cerebral infarction.
