国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2008年
11期
845-848
,共4页
癌,肝细胞%星形细胞%细胞交流
癌,肝細胞%星形細胞%細胞交流
암,간세포%성형세포%세포교류
Carcinoma,hepatocellular%Astrocytes%Cell communication
肝星状细胞(HSC)是肝纤维化及正常肝脏中细胞外基质的主要来源.慢性肝损伤时,HSC发生表犁变化转变成肌纤维母细胞,引起肝纤维化.肝细胞癌是多因素疾病,基质中有明显星状细胞浸润.探讨肝细胞癌与HSC相互作用关系可为肝细胞癌的治疗提供新思路.
肝星狀細胞(HSC)是肝纖維化及正常肝髒中細胞外基質的主要來源.慢性肝損傷時,HSC髮生錶犛變化轉變成肌纖維母細胞,引起肝纖維化.肝細胞癌是多因素疾病,基質中有明顯星狀細胞浸潤.探討肝細胞癌與HSC相互作用關繫可為肝細胞癌的治療提供新思路.
간성상세포(HSC)시간섬유화급정상간장중세포외기질적주요래원.만성간손상시,HSC발생표리변화전변성기섬유모세포,인기간섬유화.간세포암시다인소질병,기질중유명현성상세포침윤.탐토간세포암여HSC상호작용관계가위간세포암적치료제공신사로.
Hepatic stellate cells(HSCs)are key sources of extraeellular matrix during liver fibrosis and in normal liver.During chronic injury,HSCs transform into myofibroblast-like cells,causing liver fibrosis.Hepatocellular carcinoma iS multiple factors disease.There are considerable HSCs infihration in the extracellular matrix of hepatocellular carcinoma.Investigation the interaction between HSCs and hepatocellular carcinoma Can provide a new thinking of hepatocellular carcinoma therapy.
