CAJ | 학술논문

目的:对黄山乌头中二萜生物碱类化合物进行研究.方法:应用离子交换树脂法提取黄山乌头总生物碱,经色谱法分离、纯化,光谱数据和理化性质确定各化合物的结构.结果:分离得到3个化合物,分别鉴定为海帕乌头碱(Hypaconitine,1),中乌头碱(mesaconitine,2),尼奥宁(Neoline,3).结论:3个化合物均为首次从该植物中得到,双酯型乌头碱(1,2)为黄山乌头主要生物碱成分.
목적:대황산오두중이첩생물감류화합물진행연구.방법:응용리자교환수지법제취황산오두총생물감,경색보법분리、순화,광보수거화이화성질학정각화합물적결구.결과:분리득도3개화합물,분별감정위해파오두감(Hypaconitine,1),중오두감(mesaconitine,2),니오저(Neoline,3).결론:3개화합물균위수차종해식물중득도,쌍지형오두감(1,2)위황산오두주요생물감성분.
AIM: To study the diterpenoid alkaloids of the radix of Aconitum carmichaeli var. hwangshanicum.METHOD: The total alkaloids obtained by ion exchange resin were subjected to chromatography to afford three norditerpenoid alkaloids. Their structures were elucidated mainly by spectroscopic methods. RESULTS: Three major compounds: hypaconitine (1), mesaconitine (2), neoline (3) have been isolated from Aconitum carmichaeli var. hwangshanicum. CONCLUSION: Compounds 1 ～ 3 have been obtained from Aconitum carmichaeli var. hwangshanicum for the first time. Compounds 1 and 2 containing C(14)-benzoate and C(8)-acetate group were major alkaloids in this plant.