CAJ | 학술논문

　　目的研究内镜下应用多环黏膜切除术（multiband mucosectomy，MBM）治疗Barrett食管。方法采用前瞻性研究的方法，在窄波成像（narrow band imaging，NBI）下确认Barrett食管病变范围，用多环黏膜切除器吸引病灶，套扎橡皮圈后用圈套器电切。3个月复查胃镜，评估疗效。结果134例Barrett食管患者共切除病灶206块。急性并发症出血发生率6.7%（9/134），无一例发生穿孔。术后30d内（迟发性并发症）出血发生率1.5%（2/134），出现食管狭窄症状39.8%（53/133）；30d后（远期并发症）主要为食管狭窄，发生率2.3%（3/133）。术后3个月复查胃镜，病灶完整切除率98.5%（131/133）。结论内镜下MBM术治疗Barrett食管，简便、安全、有效。
　　목적연구내경하응용다배점막절제술（multiband mucosectomy，MBM）치료Barrett식관。방법채용전첨성연구적방법，재착파성상（narrow band imaging，NBI）하학인Barrett식관병변범위，용다배점막절제기흡인병조，투찰상피권후용권투기전절。3개월복사위경，평고료효。결과134례Barrett식관환자공절제병조206괴。급성병발증출혈발생솔6.7%（9/134），무일례발생천공。술후30d내（지발성병발증）출혈발생솔1.5%（2/134），출현식관협착증상39.8%（53/133）；30d후（원기병발증）주요위식관협착，발생솔2.3%（3/133）。술후3개월복사위경，병조완정절제솔98.5%（131/133）。결론내경하MBM술치료Barrett식관，간편、안전、유효。
Objective We studied the method of multiband mucosectomy(MBM)for endoscopic treatment of Barrett esophagus. The aim was to evaluate the safety and efficacy of the MBM for complete endoscopic removal of Barrett's esophagus. Methods Prospective registration of all MBM procedures in Barrett's esophagus was carried out between June 2011 and October 2012 in our hospitals. Prior to MBM,the target area was delineated with narrow band imaging(NBI). The delineated area was completely resected by MBM..Endoscopy was re-checked in 3 months to evaluate. Result A total of 206 MBM procedures were performed in 134 patients. The only acute complication was bleeding(in 6.7%,endoscopically managed). There was no perforation occurred despite absence of submucosal lifting. Early complications consisted of delayed bleeding(in 1.5%, endoscopically managed)and stenosis which occurred in 39.8% of patients(most managed by medicine). There are 2.3% of patients who were treated in a(stepwise)radical resection protocol occurred the long-term complication of stenosis. Complete endoscopic resection was achieved in 98.5% of the study. Conclusion MBM is a safe and effective technique for treatment in Barrett's esophagus.