CAJ | 학술논문

目的探讨“醒脑开窍”针刺法治疗脑梗死的机理。方法以热凝法阻断大鼠一侧大脑中动脉(MCAo)造成局灶性脑缺血为实验模型，用免疫组化法观察缺血区脑组织c-fos蛋白的动态化及针刺的干预作用。结果针刺能增强各时段c-fos蛋白的表达，提高神经细胞的应激能力和对脑缺血损伤产生适应性变化，增强脑组织的修复能力，且醒脑组优于常规组。结论“醒脑开窍”针法作用优于常规针刺法。
목적탐토“성뇌개규”침자법치료뇌경사적궤리。방법이열응법조단대서일측대뇌중동맥(MCAo)조성국조성뇌결혈위실험모형，용면역조화법관찰결혈구뇌조직c-fos단백적동태화급침자적간예작용。결과침자능증강각시단c-fos단백적표체，제고신경세포적응격능력화대뇌결혈손상산생괄응성변화，증강뇌조직적수복능력，차성뇌조우우상규조。결론“성뇌개규”침법작용우우상규침자법。
Objective TO study the mechanism of xingnao kaiqiao acupuncture for brain occlusion. Method using one-side middle cerebral artery occlusion (MCAo) rats by thermoregulation as focal cerebral ischemis experimental animal. The dynamic changes of c-fosprotein in sichemic region of brain tissue were observed by imnunohistochemitry method. Meanwhile the effect of acupuncture was stud-ied. Result The outcome of xingnao kaiqiao group was better than that of rourine group. Acupuncture could enhance the expression of c-fosprotein in all stages of ischemia, promote the stress ability of neuron produce adaptive changes to brain sichemia and improve recovery of braintissue. Conclusion The dffect of xingnao kaiqiao acupuncture was better than that of routine acupuncture.