CAJ | 학술논문

目的：研究七叶皂甙治疗高血压脑出血的疗效和对患者脑血流量的影响。方法：70例脑出血患者随机分为2组(各35例)。对照组常规治疗，治疗组加用七叶皂甙20 mg溶于生理盐水500 ml中静滴，每日1次，共10日。2组降压、抗感染等治疗相同。治疗前及3周后均测定患者的脑血流量和血液流变学变化。结果：治疗3周后，治疗组总有效率(94.3％) 高于对照组（77.1％），P<0.05；2组脑血流量和血液流变性虽均明显改善，但以七叶皂甙组尤佳，且颅内血肿吸收优于对照组。结论：七叶皂甙可有效治疗高血压脑出血。
목적：연구칠협조대치료고혈 압뇌출혈적료효화대환자뇌혈류량적영향。방법：70례뇌출혈환자수궤분위2조(각35례)。대조조상규치료，치료조가 용칠협조대20 mg용우생리염수500 ml중정적，매일1차，공10일。2조강압、항감염등치료 상동。치료전급3주후균측정환자적뇌혈류량화혈액류변학변화。결과：치 료3주후，치료조총유효솔(94.3％) 고우대조조（77.1％），P<0.05；2조뇌혈류 량화혈액류변성수균명현개선，단이칠협조대조우가，차로내혈종흡수우우대조조。결론：칠협조대가유효치료고혈압뇌출혈。
Objective:To study the influence of βaescin natrum on cerebral blood flow(CBF) in patients with cerebral hemorrhage and the c urative effects.Methods:Seventy cases with acute cerebral hemorrhage were randomly divided into two grou ps.The control group(n=35) was treated with conventional therapy while the t reatment group(n=35) based on the same therapy as control group the βaescin natrum 20 mg+normal saline 500 ml infused intravenously once a day were used for 10 days.In addition the same hypotensive,hypoglycemic and antiinfectious therapies were given to both groups.Before and after therapy th e volume of CBF and the blood rheology were detected.Results:After 3 weeks therapy the total effective rate was 94.3% in treatment group but it was 77.1% in control group.In comparison between two groups the difference was significant(P<0.05).The volume of CBF and blood rheology in both two g roups showed obvious improvements but in treatment group they were the best.Conclusions:The treatment with βaescin natrum combined with conventional therap y for cerebral hemorrhage is superior to that with conventional therapy alone.