CAJ | 학술논문

目的：探讨头孢曲松钠对急性非复杂性泌尿系感染的临床疗效。方法：采用前瞻、随机和对照的设计方案，符合入选标准的40例中、重度泌尿系统感染患者纳入本研究。研究组给予头孢曲松钠1 g/d，对照组给予环丙沙星0.4g/d。对比研究在血尿白细胞、细菌清除率、耐药性和临床体征等方面的变化。结果：研究组的细菌清除率和耐药性均优于对照组；对血尿中白细胞的影响以及临床体征的改善等研究组效果明显好于对照组，尤其在用药3 d时有显著性差异。结论：用头孢曲松钠1 g/d治疗急性非复杂性泌尿系感染是一种较好的方法。
목적：탐토두포곡송납대급성비복잡성비뇨계감염적 림상료효。방법：채용전첨、수궤화대조적설계방안，부합입선표준 적40례중、중도비뇨계통감염환자납입본연구。연구조급여두포곡송납1 g/d，대조조급여 배병사성0.4g/d。대비연구재혈뇨백세포、세균청제솔、내약성화림상체정등방면적변화。 결과：연구조적세균청제솔화내약성균우우대조조；대혈뇨중백세포적영향이급 림상체정적개선등연구조효과명현호우대조조，우기재용약3 d시유현저성차이 。결론：용두포곡송납1 g/d치료급성비복잡성비뇨계감염시일충교호적방법。
Objective:To study the efficacy of ceftriaxone in tr eatment of acute non-complicated urinary tract infections.Methods :The prospective,randomized,and controlled study was conducted in 40 patients wi th acute severe urinary tract infections.They were equally allocated to receive once daily 1g ceftriaxone or once daily 0.4g ciprofloxacin.Their blood and urine leucocytes,bacterial eliminating rate,drug resistance,and clinical presentation in both groups were observed.Results:The bacterial eliminating ra te and drug resistance of the active group were superior to that of the control group.And the influence on blood and urine leucocyte and improvement in clinica l presentations of the active group were better than that of the control group,s ignificant difference in these parameters was observed at the third day of treat ment.Conclusion:Ceftriaxone is an effective agent for treatment of acute non-complicated urinary tract infections in once daily dose of 1g.