CAJ | 학술논문

目的：观察甘露醇对降低人工晶体植入术后并发症的临床效果。方法：将526例、618眼人工晶体植入术随机分为A、B 2组，A组为甘露醇治疗组，B组为对照组用醋氮酰胺治疗，分别对2组患者的术后眼压、前房反应、后囊混浊等进行观察分析。结果：术后72h内2组患者高眼压的发生率差异无显著性(P＞0.05)，而间断性低眼压的发生率A组高于B组，差异有高度显著性(P＜0.01)。A组中6、24、48h眼压为甘露醇用药2h内的眼压，其眼压平均值均低于B组同一时间的眼压平均值，差异有显著性(P＜0.01，P＜0.05)。前房反应A组的发生率低于B组，平均随访15.7个月，后囊混浊的发生率，A组低于B组，差异有高度显著性(P＜0.01)。结论：甘露醇用于人工晶体植入术后，不仅有预防术后高眼压的作用，而且对促进前房反应的消退，降低后囊混浊的发生有明显效果。
목적：관찰감로순대강저인공정체식입술후병발증적림상효과。방법：장526례、618안인공정체식입술수궤분위A、B 2조，A조위감로순치료조，B조위대조조용작담선알치료，분별대2조환자적술후안압、전방반응、후낭혼탁등진행관찰분석。결과：술후72h내2조환자고안압적발생솔차이무현저성(P＞0.05)，이간단성저안압적발생솔A조고우B조，차이유고도현저성(P＜0.01)。A조중6、24、48h안압위감로순용약2h내적안압，기안압평균치균저우B조동일시간적안압평균치，차이유현저성(P＜0.01，P＜0.05)。전방반응A조적발생솔저우B조，평균수방15.7개월，후낭혼탁적발생솔，A조저우B조，차이유고도현저성(P＜0.01)。결론：감로순용우인공정체식입술후，불부유예방술후고안압적작용，이차대촉진전방반응적소퇴，강저후낭혼탁적발생유명현효과。
Objective:To observe the effect for mannitol to reduce the complication after IOL implant.Method:The IOL were implanted on 618 eyes which were divided randomly into groups of A and B. The intraocular pressure (IOP),the anterior reactions and the after-cataract were compared and analysed.Results:The incidence of the high IOP was found nonsignificant difference between A group using drug mannitol and B group using drug diamox within 72 hours after the operation (P＞0.05).However the incidence of the lower IOP on A group was higher than that on B group(P＜0.01).The IOPs of the postoperative 6th,24th,48th hours were the same with the IOPs after using mannitol in 2 hours in group A and the mean IOP in group A was lower than that in group B(P＜0.01and P＜0.05).Through observation about 15.7 months，the incidence of after-cataract in A group was lower than that in group B(P＜0.01).Conclusion:The drug mannitol can not only prevent the high IOP after IOL implant but also reduce the anterior reactions as well as the after-cataract.