中国中医基础医学杂志
中國中醫基礎醫學雜誌
중국중의기출의학잡지
CHINESE JOURNAL OF BASIC MEDICINE IN ADITIONAL CHINESE MEDICINE
2001年
1期
49-51
,共3页
王杰超%孙喜元%李海滨%吕晓红%刘翠绵%刘翠青%张刚%霍猛%王文娟%王丽君
王傑超%孫喜元%李海濱%呂曉紅%劉翠綿%劉翠青%張剛%霍猛%王文娟%王麗君
왕걸초%손희원%리해빈%려효홍%류취면%류취청%장강%곽맹%왕문연%왕려군
通心络胶囊%无症状心肌缺血%动态心电图%踏车运动试验
通心絡膠囊%無癥狀心肌缺血%動態心電圖%踏車運動試驗
통심락효낭%무증상심기결혈%동태심전도%답차운동시험
目的：探讨更适合冠心病无症状心肌缺血患者长期服用的药物。方法：采用随机双盲法，对经动态心电图证实为无症状心肌缺血的冠心病患者138例，对照观察了通心络胶囊和硝酸异山梨醇治疗无症状心肌缺血的疗效。结果：通心络胶囊在减少无症状心肌缺血发生次数和持续时间方面明显优于硝酸异山梨醇(P＜0.01)。其运动持续时间、诱发心绞痛发作时间、ST段压低≥1mm所需时间均显著延长，运动耐力增加(P＜0.01)。结论：通心络胶囊更适合冠心病无症状心肌缺血患者长期服用。
目的：探討更適閤冠心病無癥狀心肌缺血患者長期服用的藥物。方法：採用隨機雙盲法，對經動態心電圖證實為無癥狀心肌缺血的冠心病患者138例，對照觀察瞭通心絡膠囊和硝痠異山梨醇治療無癥狀心肌缺血的療效。結果：通心絡膠囊在減少無癥狀心肌缺血髮生次數和持續時間方麵明顯優于硝痠異山梨醇(P＜0.01)。其運動持續時間、誘髮心絞痛髮作時間、ST段壓低≥1mm所需時間均顯著延長，運動耐力增加(P＜0.01)。結論：通心絡膠囊更適閤冠心病無癥狀心肌缺血患者長期服用。
목적：탐토경괄합관심병무증상심기결혈환자장기복용적약물。방법：채용수궤쌍맹법，대경동태심전도증실위무증상심기결혈적관심병환자138례，대조관찰료통심락효낭화초산이산리순치료무증상심기결혈적료효。결과：통심락효낭재감소무증상심기결혈발생차수화지속시간방면명현우우초산이산리순(P＜0.01)。기운동지속시간、유발심교통발작시간、ST단압저≥1mm소수시간균현저연장，운동내력증가(P＜0.01)。결론：통심락효낭경괄합관심병무증상심기결혈환자장기복용。
Objective: To observe the effect of Tongxinluo Capsules(TXLC)in treating silent myocardial ischemia (SMI)of coronary artery disease. Methods:The effect of oral TXLC and Sordi were compared with those of placebo in 138 patients with coronary artery disease and SMI. Patients performed ambulatory electrocardiographic monitoring and bicycle ergometic exercise, after 8 weeks periods treatment of 4 pills, three times daily, 10～15mg Sordi, three times daily, and placebo. All drugs were given double blind and randomly. Results:TXLC not only appeared to be more effective than Sordi in reducing the number and duration of SMI, but also increasing exercise duration and delaying time of exercise angina or peak effort(P＜0.01). Conclusion:TXLC is a more effective drug in treating coronary artery disease and SMI.
