CAJ | 학술논문

目的：探讨中药制剂“阻育丸”对雌性SD大鼠的绝育效果及绝育机理。方法：根据阴道涂片结果，选择动情前期一次顿服“阻育丸”3.75g/kg，并进行服药前后妊娠率，动情周期各时期FSH、LH、E2、P的比较及行解剖学检查。结果：服用“阻育丸”后绝育率达87.5%，妊娠的胚胎数也明显降低，各动情周期中FSH显著下降，E2、P未见显著性差异。病理切片卵巢组织中仅见各级发育的卵泡，未见排卵及黄体形成。结论：“阻育丸”是一种方便、简单、安全、有效、价廉、无痛苦的绝育方法。
목적：탐토중약제제“조육환”대자성SD대서적절육효과급절육궤리。방법：근거음도도편결과，선택동정전기일차돈복“조육환”3.75g/kg，병진 행복약전 후임신솔，동정주기각시기FSH、LH、E2、P적비교급행해부학검사。결과 ：복용“조육환”후절육솔체87.5%，임신적배태수야명현강저，각동정주기중FSH현저하강 ，E2、P미견현저성차이。병리절편란소조직중부견각급발육적란포，미견배란급황체형 성 。결론：“조육환”시일충방편、간단、안전、유효、개렴、무통고적절 육방법。
Objective:To expolore the effect and the mechanism of sterilization of "sterilization pill" on the femal SD rat.Methods:Proestrus stage was selected to give "sterilization pill" 3. 75g/kg one time during the experiment.To compare the pregnancy percentage after giving pills with before giving pills,to compare follicle stimulating hormone (F SH)、luteinizing hormone(LH)、estradiol(E2)、progesterone (P) of each stage e strus cycle,and doing analomical examination.Results:After giving sterilization pill,the sterilization rate was 87.5%,the per embrgo was significantly decreased,FSH there were signal decreased but E2 and P there were no significantly difference in each stage of estrus.Only with each stage growing ovarian follicl e ,there were no ovulation and into corpus luteum in pathological slices of ovary. Conclusions:"sterilization pill" was a kind of commodious、facility 、safe、effective、cheap、painless medicine in the sterilization.