CAJ | 학술논문

目的了解社区高血压病人药物利用与依从性状况。方法利用专门拟定的调查表由调查员入户调查。结果 973名社区高血压病人中有78.6%的服用一种药物。常用的五种药物是珍菊降压片(34.12%)、硝苯地平(23.12%)、复方降压片(21.07%)、卡托普利(10.07%)与倍他乐克(5.56%)。常用药物类型为复方制剂（58.97%）、钙拮抗剂（34.05%）、ACE阻滞剂（12.82%）。高血压病人中依从性佳的比例为31.1%，服用一种药物组依从性优于服用二种药物组（OR=1.72，95%CI 1.13～2.72）。交感神经阻滞剂的依从性显著优于复方制剂（OR=2.84，95%CI 1.18～6.92）。结论:社区高血压病人用药仍以复方制剂为主，其有助于改善病人依从性。建议开发长效复方制剂。
목적 료해사구고혈압병인약물이용여의종성상황。 방법 이용전문의정적조사표유조사원입호조사。 결과 973명사구고혈압병인중유78.6%적복용일충약물。상용적오충약물시진국강압편(34.12%)、초분지평(23.12%)、복방강압편(21.07%)、잡탁보리(10.07%)여배타악극(5.56%)。상용약물류형위복방제제（58.97%）、개길항제（34.05%）、ACE조체제（12.82%）。고혈압병인중의종성가적비례위31.1%，복용일충약물조의종성우우복용이충약물조（OR=1.72，95%CI 1.13～2.72）。교감신경조체제적의종성현저우우복방제제（OR=2.84，95%CI 1.18～6.92）。 결론:사구고혈압병인용약잉이복방제제위주，기유조우개선병인의종성。건의개발장효복방제제。
Objective To survey the use of anti-hypertensive and to evaluate the compliance of patients at community. Method To interview patients at home with special questionnaire. Results There are 78.6% patients taking a kind of medicine in 973 patients. The five drugs of the most generally used,such as Zhengju in 34.12%,nifedipine in 23.12%, combination of drugs in 21.07%, captopril in 10.07%,metoprolol in 5.56%. The groups of the most commonly used medicine are compound preparation of antihypertension(58.97%), calcium antagonsis(34.05%), ACEI(12.82%). The compliance of taking one kinds of medicine group is better than taking two kinds medicine group(OR=1.72, 95%CI 1.13～2.72）. The compliance of sympathetic nerve blockers is significantly better than combined antihy pertensive drugs（OR=2.84，95%CI 1.18～6.92）. Conclusion:The compound medicine of antihypertension is mainly taken by patients in community, which is helpful to improve the compliance of patients. So some new long effect of compound drug must be developed in future.