CAJ | 학술논문

目的观察氟桂嗪治疗偏头痛患者脑血流的变化及疗效。方法采用经颅多普勒超声(TCD)技术，检测60例偏头痛患者颅内动脉血流速度，并应用氟桂嗪治疗前后作自身对照。结果偏头痛患者治疗前颅内动脉的平均血流速度(Vm)明显快于健康对照组(P＜0.01)；治疗后平均血流速度明显减慢，与治疗前比较差异有显著性(P＜0.05，P＜0.01)，与健康对照组比较差异无显著性(P＞0.05)。临床治疗总有效率为88.33%。结论氟桂嗪能改善偏头痛患者颅内动脉的机能状态，疗效确切。
목적관찰불계진치료편두통환자뇌혈류적변화급료효。방법채용경로다보륵초성(TCD)기술，검측60례편두통환자로내동맥혈류속도，병응용불계진치료전후작자신대조。결과편두통환자치료전로내동맥적평균혈류속도(Vm)명현쾌우건강대조조(P＜0.01)；치료후평균혈류속도명현감만，여치료전비교차이유현저성(P＜0.05，P＜0.01)，여건강대조조비교차이무현저성(P＞0.05)。림상치료총유효솔위88.33%。결론불계진능개선편두통환자로내동맥적궤능상태，료효학절。
Objecteves　To observe the changes of cerebral flow and therapeutic effect of flunarezine in treating patients with migraine.Methods　60 cases with megraine were detected by transcranial doppler(TCD)for the flow velocity of the intracranial artery，and made comparisons between before and after treatment with flunarizine.Results　The mean velocity(Vm)of the intracranial artery in migraine were significantly faster before treatment than healthy controls(P＜0.01).The mean velocity of the cerebal artery in migraine slowed down after treatment，there were marked difference between before and after treatment with Flunarizine(P＜0.01，P＜0.05).However the Vm of cerebral artery were insignificant between after treatment and healthy controls(P＞0.05).The clinical total effective rate was 88.33%.Conclusions　Flunarizine can improve vascular functional conditions of the intracranial artery in migraine and may achieve an obvious effect.