CAJ | 학술논문

目的探讨结直肠癌术后吻合口瘘发生的高危因素,为预防吻合口瘘的发生提供依据.方法选取916例结直肠癌术后发生吻合口瘘的53例患者为研究对象,对患者全身、局部因素与吻合口瘘发生的相关性进行统计分析.结果结直肠癌患者全身因素中年龄、ASA分级、血红蛋白、红细胞、总蛋白及空腹血糖与吻合口瘘发生存在相关性(P<0.05),局部因素中的吻合方式、吻合口张力、引流管放置位置、术前有无肠梗阻、术前有无腹腔感染及肿瘤分化程度与吻合口瘘发生存在相关性(P<0.05).结论结直肠癌术后引起吻合口瘘发生的高危因素较多,应做好围手术期的各项工作.
목적 탐토결직장암술후문합구루발생적고위인소,위예방문합구루적발생제공의거.방법 선취916례결직장암술후발생문합구루적53례환자위연구대상,대환자전신、국부인소여문합구루발생적상관성진행통계분석.결과 결직장암환자전신인소중년령、ASA분급、혈홍단백、홍세포、총단백급공복혈당여문합구루발생존재상관성(P<0.05),국부인소중적문합방식、문합구장력、인류관방치위치、술전유무장경조、술전유무복강감염급종류분화정도여문합구루발생존재상관성(P<0.05).결론 결직장암술후인기문합구루발생적고위인소교다,응주호위수술기적각항공작.
Objective To study the high risk factors of anastomotic leakage after colon cancer surgery ,so as to provide evidence for the prevention of anastomotic leakage. Methods Fifty-three patients with anastomotic leakage after colon cancer surgery of 916 cases were selected as research objects,then the correlation between systemic factors,local factors and occurrence of anastomotic leakage was analyzed and studied. Results The correlation between age, ASA grade, serum hemoglobin, red blood cell, total protein, fasting blood glucose of systemic factors except for sex and occurrence of anastomotic leakage was obvious (P< 0.05). There was correlation between the methods of anastomosis, anastomotic tension, setting position of drainage tube, intestinal obstruction, abdominal infection and degree of tumor differentiation except for with or without chemotherapy and radiotherapy and occurrence of anastomotic leakage(P < 0.05). Conclusion The high risk factors of anastomotic leakage after colon cancer surgery are multiple,and well various work should be done during perioperative period.