中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2009年
21期
4196-4200
,共5页
马建华%印佳%封林森%刘艺春%方涛%蒋峰
馬建華%印佳%封林森%劉藝春%方濤%蔣峰
마건화%인가%봉림삼%류예춘%방도%장봉
颅骨缺损%颅骨修补%三维成像%骨代用品%材料
顱骨缺損%顱骨脩補%三維成像%骨代用品%材料
로골결손%로골수보%삼유성상%골대용품%재료
目的:观察三维EH复合型人工颅骨板在修补颅骨缺损中的作用.方法:回顾性分析2004-07/2007-05泰兴市人民医院神经外科住院患者53例,男31例,女22例;年龄19~68岁,均符合颅骨修补适应证.颅骨缺损原因:创伤41例,高血压7例,肿瘤3例,动脉瘤2例.13例患者为双侧颅骨缺损.额部颅骨缺损5片(其中合并眶部严重缺损2例),颢部9片,额颞部42片,颞顶部3片,项枕部4片,额顶部3片.单片最小缺损面积为4 cm×6 cm,最大缺损面积12 cm×18 cm.全部患者均采用经螺旋CT(层厚≤5 mm)扫描、CAD三维重建成像、快速成型技术顶制的三维EH复合型人工颅骨板进行颅骨修补.观察有无切口感染、排异反应及并发症发生.结果:53例患者均获得随访,平均随访18个月.患者对塑形的满意率达100%.其中2例患者曾分别于术后4 d和1周时出现轻度皮瓣下积液,经穿刺抽吸加压包扎同时应用抗生素预防感染处理后积液于短时间内消失.未见其他颅骨修补术后常见的并发症.结论:三维EH型复合人工颅骨板具有良好的生物相容性,操作方便,外形满意,并发症少,是一种理想的颅骨修补材料.
目的:觀察三維EH複閤型人工顱骨闆在脩補顱骨缺損中的作用.方法:迴顧性分析2004-07/2007-05泰興市人民醫院神經外科住院患者53例,男31例,女22例;年齡19~68歲,均符閤顱骨脩補適應證.顱骨缺損原因:創傷41例,高血壓7例,腫瘤3例,動脈瘤2例.13例患者為雙側顱骨缺損.額部顱骨缺損5片(其中閤併眶部嚴重缺損2例),顥部9片,額顳部42片,顳頂部3片,項枕部4片,額頂部3片.單片最小缺損麵積為4 cm×6 cm,最大缺損麵積12 cm×18 cm.全部患者均採用經螺鏇CT(層厚≤5 mm)掃描、CAD三維重建成像、快速成型技術頂製的三維EH複閤型人工顱骨闆進行顱骨脩補.觀察有無切口感染、排異反應及併髮癥髮生.結果:53例患者均穫得隨訪,平均隨訪18箇月.患者對塑形的滿意率達100%.其中2例患者曾分彆于術後4 d和1週時齣現輕度皮瓣下積液,經穿刺抽吸加壓包扎同時應用抗生素預防感染處理後積液于短時間內消失.未見其他顱骨脩補術後常見的併髮癥.結論:三維EH型複閤人工顱骨闆具有良好的生物相容性,操作方便,外形滿意,併髮癥少,是一種理想的顱骨脩補材料.
목적:관찰삼유EH복합형인공로골판재수보로골결손중적작용.방법:회고성분석2004-07/2007-05태흥시인민의원신경외과주원환자53례,남31례,녀22례;년령19~68세,균부합로골수보괄응증.로골결손원인:창상41례,고혈압7례,종류3례,동맥류2례.13례환자위쌍측로골결손.액부로골결손5편(기중합병광부엄중결손2례),호부9편,액섭부42편,섭정부3편,항침부4편,액정부3편.단편최소결손면적위4 cm×6 cm,최대결손면적12 cm×18 cm.전부환자균채용경라선CT(층후≤5 mm)소묘、CAD삼유중건성상、쾌속성형기술정제적삼유EH복합형인공로골판진행로골수보.관찰유무절구감염、배이반응급병발증발생.결과:53례환자균획득수방,평균수방18개월.환자대소형적만의솔체100%.기중2례환자증분별우술후4 d화1주시출현경도피판하적액,경천자추흡가압포찰동시응용항생소예방감염처리후적액우단시간내소실.미견기타로골수보술후상견적병발증.결론:삼유EH형복합인공로골판구유량호적생물상용성,조작방편,외형만의,병발증소,시일충이상적로골수보재료.
OBJECTIVE: To observe effects of three-dimensional EH composite template on repairing cranial bone defect.
METHODS: A total of 53 inpatients were analyzed retrospectively at the Department of Neurosurgery, Taixing People's Hospital from July 2004 to May 2007, comprising 31 males and 22 females, aged 19-68 years. They were in accordance with cranial repairing indication. Reasons for skull defect: traumatic brain injury (41 cases), hypertension (7 cases), intracranial cancer (3 cases), intracranial aneurysm (2 cases). Thirteen patients developed bilateral cranial defect. The defect region: frontal (5 slices, comprising 2 with severe orbital part defect), temporal (9 slices), frontotemporal (42 slices), temporoparietal (3 slices), parietoocipital (4 slices), frontoparietal (3 slices). The smallest single-chip defect size was 4 cm × 6 cm, and the largest one was 12 cm×18 cm. All the patients were mended by three-dimensional EH composite template using spiral CT (≤5 mm thickness) scanning, CAD three dimensional reconstruction, quickly modeling technique. Infection of incisional wound, rejection and complications were observed.
RESULTS: A total of 53 patients were followed up, with an average follow-up period of 18 months, and all of them were satisfied with the shapes (100%). Mild collection of the fluid under the scalp was found in 2 cases 4 days and 1 week following surgery, and disappeared after suction and pressure dressing. No other frequent complications were observed after cranioplasty.
CONCLUSION: Three-dimensional EH composite template is an ideal material for cranial bone defect, because of its good biocompatibility, easy operation, good postoperative shape and less complications.