湖北农业科学
湖北農業科學
호북농업과학
2009年
10期
2516-2518,2525
,共4页
范国英%钟华%王建国%乔盼盼
範國英%鐘華%王建國%喬盼盼
범국영%종화%왕건국%교반반
中药合成制剂%免疫抗毒散%药效%免疫抑制
中藥閤成製劑%免疫抗毒散%藥效%免疫抑製
중약합성제제%면역항독산%약효%면역억제
Chinese crude drug%the powder of immunity anti-virus%pharmacodynami%immunological inhibition
选用中药合成制剂"免疫抗毒散",通过对猪瘟的抗体效价增强试验、鸡胚攻毒试验、雏鸡人工发病试验、抑菌试验以及对小白鼠免疫器官的影响试验,验证了该中药制剂的药效作用.结果表明,"免疫抗毒散"能提高畜禽的抗体水平,具有杀灭病毒、保护胚胎的作用;能提高雏鸡的抗病能力,降低发病率和死亡率;对革兰氏阳性菌、革兰氏阴性菌均有较强的抑菌作用,其最小菌浓度为4mg·mL~(-1);并能促进小白鼠免疫器官的发育.
選用中藥閤成製劑"免疫抗毒散",通過對豬瘟的抗體效價增彊試驗、鷄胚攻毒試驗、雛鷄人工髮病試驗、抑菌試驗以及對小白鼠免疫器官的影響試驗,驗證瞭該中藥製劑的藥效作用.結果錶明,"免疫抗毒散"能提高畜禽的抗體水平,具有殺滅病毒、保護胚胎的作用;能提高雛鷄的抗病能力,降低髮病率和死亡率;對革蘭氏暘性菌、革蘭氏陰性菌均有較彊的抑菌作用,其最小菌濃度為4mg·mL~(-1);併能促進小白鼠免疫器官的髮育.
선용중약합성제제"면역항독산",통과대저온적항체효개증강시험、계배공독시험、추계인공발병시험、억균시험이급대소백서면역기관적영향시험,험증료해중약제제적약효작용.결과표명,"면역항독산"능제고축금적항체수평,구유살멸병독、보호배태적작용;능제고추계적항병능력,강저발병솔화사망솔;대혁란씨양성균、혁란씨음성균균유교강적억균작용,기최소균농도위4mg·mL~(-1);병능촉진소백서면역기관적발육.
The pharmacodynamic tests of the Chinese crude drug "the powder of immunity anti-virus" were studied through the enhancement experiment of swine plague antibody titer; the conteracting toxic substances experiment of chick embryo; the artificial invasion experiment of chicken; the experiment of bacteriostasis and the influence experiment of Mus musculus albus immune organ. The results indicated that "the powder of immunity anti-virus" enhanced the level of antibody titer; had the effect of killing virus and preserving embryo; enhanced the disease resistance of chicken and degraded the disease incidence and the mortality rate; had the effective bacteriostasis to Gram-positive bacteria and Gram-negative bacteria,the minimal inhibitory concentration was 4 mg·mL~(-1); and enhanced development of murine immune organ.