中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2011年
6期
460-463
,共4页
冠状动脉疾病%白细胞%血小板%预后
冠狀動脈疾病%白細胞%血小闆%預後
관상동맥질병%백세포%혈소판%예후
Coronary disease%Leukocytes%Blood platelet%Prognosis
目的 探讨急性冠状动脉综合征(ACS)患者的近期预后与影响临床预后的危险因素,为ACS患者的预后风险评估提供依据.方法 入选ACS患者156例.采用无序多分类Logistic回归分析ACS患者的基线特征因素与30 d好转、死亡、心绞痛、心力衰竭的相关性.结果 将全部变量进行多因素Logistic回归分析,显示年龄(OR=1.20,95%CI:1.07~1.34)、糖尿病(OR=19.41,95%CI:3.02~124.70)、白细胞升高(OR=11.36,95%CI:1.87~69.11)及血小板升高(OR=7.72,95%CI:1.29~46.15)是30 d死亡的独立危险因素;白细胞升高(OR=2.35,95%CI:0.89~6.17)及血脂异常(OR=6.25,95%CI:2.11~18.48)是30 d心绞痛发作的独立危险因素;年龄(OR=1.10,95%CI:1.03~1.17)、男性(OR=4.18,95%CI:0.81~21.51)、白细胞升高(OR=2.97,95%CI:1.09~8.14)及血脂异常(OR=7.69,95%CI:2.39~24.76)是30 d发生心力衰竭的独立危险因素.结论 年龄、糖尿病史、血小板升高及白细胞升高是影响ACS患者30 d死亡的独立危险因素;白细胞升高及血脂异常是影响ACS患者30 d心绞痛发作的独立危险因素;年龄、男性、白细胞升高及血脂异常是影响ACS患者30 d心力衰竭的独立危险因素.
目的 探討急性冠狀動脈綜閤徵(ACS)患者的近期預後與影響臨床預後的危險因素,為ACS患者的預後風險評估提供依據.方法 入選ACS患者156例.採用無序多分類Logistic迴歸分析ACS患者的基線特徵因素與30 d好轉、死亡、心絞痛、心力衰竭的相關性.結果 將全部變量進行多因素Logistic迴歸分析,顯示年齡(OR=1.20,95%CI:1.07~1.34)、糖尿病(OR=19.41,95%CI:3.02~124.70)、白細胞升高(OR=11.36,95%CI:1.87~69.11)及血小闆升高(OR=7.72,95%CI:1.29~46.15)是30 d死亡的獨立危險因素;白細胞升高(OR=2.35,95%CI:0.89~6.17)及血脂異常(OR=6.25,95%CI:2.11~18.48)是30 d心絞痛髮作的獨立危險因素;年齡(OR=1.10,95%CI:1.03~1.17)、男性(OR=4.18,95%CI:0.81~21.51)、白細胞升高(OR=2.97,95%CI:1.09~8.14)及血脂異常(OR=7.69,95%CI:2.39~24.76)是30 d髮生心力衰竭的獨立危險因素.結論 年齡、糖尿病史、血小闆升高及白細胞升高是影響ACS患者30 d死亡的獨立危險因素;白細胞升高及血脂異常是影響ACS患者30 d心絞痛髮作的獨立危險因素;年齡、男性、白細胞升高及血脂異常是影響ACS患者30 d心力衰竭的獨立危險因素.
목적 탐토급성관상동맥종합정(ACS)환자적근기예후여영향림상예후적위험인소,위ACS환자적예후풍험평고제공의거.방법 입선ACS환자156례.채용무서다분류Logistic회귀분석ACS환자적기선특정인소여30 d호전、사망、심교통、심력쇠갈적상관성.결과 장전부변량진행다인소Logistic회귀분석,현시년령(OR=1.20,95%CI:1.07~1.34)、당뇨병(OR=19.41,95%CI:3.02~124.70)、백세포승고(OR=11.36,95%CI:1.87~69.11)급혈소판승고(OR=7.72,95%CI:1.29~46.15)시30 d사망적독립위험인소;백세포승고(OR=2.35,95%CI:0.89~6.17)급혈지이상(OR=6.25,95%CI:2.11~18.48)시30 d심교통발작적독립위험인소;년령(OR=1.10,95%CI:1.03~1.17)、남성(OR=4.18,95%CI:0.81~21.51)、백세포승고(OR=2.97,95%CI:1.09~8.14)급혈지이상(OR=7.69,95%CI:2.39~24.76)시30 d발생심력쇠갈적독립위험인소.결론 년령、당뇨병사、혈소판승고급백세포승고시영향ACS환자30 d사망적독립위험인소;백세포승고급혈지이상시영향ACS환자30 d심교통발작적독립위험인소;년령、남성、백세포승고급혈지이상시영향ACS환자30 d심력쇠갈적독립위험인소.
Objective To explore short-term prognosis of patients with acute coronary syndrome (ACS) and prognostic risk factors, and to provide information for prognostic risk assessment. Methods A total of 156 patients with acute coronary syndrome were enrolled. The correlations of baseline characteristics with 30-day improvement, death, angina pectoris and heart failure were analyzed using unordered multivariate logistic regression. Results Logistic regression analysis showed that the independent risk factors for 30-day death included age (OR=1.20, 95%CI: 1.07-1.34), diabetes (OR=19.41, 95%CI: 3.02-124.70), leukocytosis (OR=11.36, 95%CI: 1.87-69.11) and increased platelet (OR=7.72, 95%CI: 1.29-46.15). The independent risk factors for 30-day angina pectoris included leukocytosis (OR=2.35, 95%CI: 0.89-6.17) and dyslipidemia (OR=6.25, 95%CI: 2.11-18.48). The independent risk factors for the occurrence of heart failure during 30-day post-ACS included age (OR=1.10, 95%CI: 1.03-1.17), male (OR=4.18, 95%CI: 0.81-21.51), leukocytosis (OR=2.97, 95%CI: 1.09-8.14) and dyslipidemia (OR=7.69, 95%CI: 2.39-24.76). Conclusions Age, diabetes, leukocytosis and increased platelet are independent risk factors associated with 30-day death; Leukocytosis and dyslipidemia are independent risk factors associated with 30-day angina pectoris; Age, male, leukocytosis and dyslipidemia are the independent risk factors associated with 30-day heart failure.