CAJ | 학술논문

目的:探讨FDG PET/CT在经典型不明原因发热中的诊断价值.方法:对在2007年10月至2009年10月间27例(男性19例,女性8例)经典型不明原因发热病例,行FDG PET/CT显像,PET/CT图像结果判断应用目测法和半定量分析方法.最终诊断包括病理学检查或临床随访.结果:纳入本研究共27例不明原因发热患者,行PET/CT检查后经病理穿刺或病例随访证实,引起不明原因发热的病因共21例,其中包括感染10例,肿瘤性疾病(淋巴瘤)4例,非感染性炎症4例,其他类型3例,未能发现病因6例.FDG PET/CT诊断真阳性21例,假阳性1例,假阴性0例,真阴性5例.灵敏度100%,特异性83.3%;阳性预测值95.5%,阴性预测值100%;准确性96.3%.结论:在诊断不明原因发热患者中,FDG PET/CT显像是灵敏可靠的诊断方法,建议常规检查未能发现病灶或不能确诊的病例,可尽早行FDG PET/CT显像.
목적:탐토FDG PET/CT재경전형불명원인발열중적진단개치.방법:대재2007년10월지2009년10월간27례(남성19례,녀성8례)경전형불명원인발열병례,행FDG PET/CT현상,PET/CT도상결과판단응용목측법화반정량분석방법.최종진단포괄병이학검사혹림상수방.결과:납입본연구공27례불명원인발열환자,행PET/CT검사후경병리천자혹병례수방증실,인기불명원인발열적병인공21례,기중포괄감염10례,종류성질병(림파류)4례,비감염성염증4례,기타류형3례,미능발현병인6례.FDG PET/CT진단진양성21례,가양성1례,가음성0례,진음성5례.령민도100%,특이성83.3%;양성예측치95.5%,음성예측치100%;준학성96.3%.결론:재진단불명원인발열환자중,FDG PET/CT현상시령민가고적진단방법,건의상규검사미능발현병조혹불능학진적병례,가진조행FDG PET/CT현상.
Objective: To evaluate the application of ~(18)F-FDG PET/CT in diagnosis of classic fever of unknown origin. Methods: A total of 27 consecutive patients with classic fever of unknown origin (FUO) (19 men,8 women; aged 24-82 y) underwent ~(18)F-FDG PET/CT scans.The images were interpreted by visual inspection and semiquantitative analysis (standardized uptake value,SUV).Final diagnosis was based on histopathology or clinical follow-up. Results: The cause of FUO was confirmed by followed investigations in 21 of 27 cases after PET/CT scan,including 10 cases of infection,4 of noninfectious inflammation,4 of malignancies and 3 of miscellaneous disorders; and remaining 6 cases were still confirmed FUO.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy were 100.0%,83.3%,83.3%,100.0% and 96.3%,respectively. Conclusion: For patients with fever of unknown origin,~(18)F-FDG-PET/CT can be a sensitive,reliable imaging modality.It is suggested that ~(18)F-FDG-PET/CT should be considered earlier in detecting the causes of FUO,which is difficultly diagnosed by conventional modalities.