中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2009年
4期
307-311
,共5页
朱永城%江慧琳%陈晓辉%林珮仪%王华军%李缨
硃永城%江慧琳%陳曉輝%林珮儀%王華軍%李纓
주영성%강혜림%진효휘%림패의%왕화군%리영
插管法%气管内%大鼠%光纤%成功率%存活率
插管法%氣管內%大鼠%光纖%成功率%存活率
삽관법%기관내%대서%광섬%성공솔%존활솔
Intuhation%intratracheal%Rats%Optical fiber%Success rate%Survival rate
目的 利用气管导管内置入直径0.9 mm的光纤作为光源,建立一种新的大鼠经口气管插管方法 .方法 SD大鼠40只分2组:(1)气管导管内置入光纤引导下的经口气管插管组(光纤组,n=20),(2)传统光源直视下的经口气管插管组(传统组,n=20).比较2组经口气管插管时间、插管次数、一次插管成功率、拔除气管插管后l周的存活率.结果 光纤组的插管时间(36.00±16.43)s、插管次数(1.05±0.22)次、一次插管成功率95%均优于传统组[(86.20±56.48)s,(1.75±1.02)次,60%,P<0.05],但2组大鼠拔管1周后的存活率差异无统计学意义.结论 气管导管内置光纤引导下的经口气管插管法是一种创新的大鼠气管插管方法 ,能实现快速、有效、准确的气管插管.
目的 利用氣管導管內置入直徑0.9 mm的光纖作為光源,建立一種新的大鼠經口氣管插管方法 .方法 SD大鼠40隻分2組:(1)氣管導管內置入光纖引導下的經口氣管插管組(光纖組,n=20),(2)傳統光源直視下的經口氣管插管組(傳統組,n=20).比較2組經口氣管插管時間、插管次數、一次插管成功率、拔除氣管插管後l週的存活率.結果 光纖組的插管時間(36.00±16.43)s、插管次數(1.05±0.22)次、一次插管成功率95%均優于傳統組[(86.20±56.48)s,(1.75±1.02)次,60%,P<0.05],但2組大鼠拔管1週後的存活率差異無統計學意義.結論 氣管導管內置光纖引導下的經口氣管插管法是一種創新的大鼠氣管插管方法 ,能實現快速、有效、準確的氣管插管.
목적 이용기관도관내치입직경0.9 mm적광섬작위광원,건립일충신적대서경구기관삽관방법 .방법 SD대서40지분2조:(1)기관도관내치입광섬인도하적경구기관삽관조(광섬조,n=20),(2)전통광원직시하적경구기관삽관조(전통조,n=20).비교2조경구기관삽관시간、삽관차수、일차삽관성공솔、발제기관삽관후l주적존활솔.결과 광섬조적삽관시간(36.00±16.43)s、삽관차수(1.05±0.22)차、일차삽관성공솔95%균우우전통조[(86.20±56.48)s,(1.75±1.02)차,60%,P<0.05],단2조대서발관1주후적존활솔차이무통계학의의.결론 기관도관내치광섬인도하적경구기관삽관법시일충창신적대서기관삽관방법 ,능실현쾌속、유효、준학적기관삽관.
Objective To develop a new method of orotracbeal intubation in adult rats by using a 0.9 mm-in optical fiber-laying in the tracheal catheter as a source of light. Methods Sprague-Dawley rats were randomly divivded into two groups for orotracbeal intubation: (1) the optical fiber group (n=20): an optical fiber was utilized as a light to visualize the trachea and vocal cords; (2)the conventional group (n= 20): a comprehensive rodent model of orotracheal intuhation was developed. The intubation time and intuhation frequency, the success rate of the first intubation were compared between the optical fiber group and the conventional group. After intubation the rats were mechanically ventilated for 60 min, with the tidal volume at 0.65 ml/100 g and respiratory frequency at 60/rain. And then the endotracheal tube was removed, the survival rate was compared between two groups in 1 week. Results The time and frequency of intubation were significantly less in the optical fiber group than those in the conventional group [(36.00±16.43) s vs (86.20±56.48) s, 1.05±0.22 vs 1.75±1.02, P<0.05)]. The success rate of the first intuhation in the optical fiber group was obviously higher than that of the optical fiber group (95% vs 60%, P<0.05). There was no obviously difference in the survival rate after extuhation in 1 week between groups (100% vs 80%, P>0.05). Conclusion The improved orotracheal intubation technique with optical fiber is a method of innovation, which can obtain a quick, effective and accurate intubation.