国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2011年
9期
670-673
,共4页
鼻咽肿瘤%放射疗法%药物疗法
鼻嚥腫瘤%放射療法%藥物療法
비인종류%방사요법%약물요법
Nasopharyngeal neoplasms%Radiotherapy%Drug therapy
鼻咽癌(NPC)对放化疗敏感,联合放化疗可使大多数局部晚期NPC的生存获益,但仍有部分患者因联合放化疗引起的严重不良反应而未能达到生存获益.因此,在权衡治疗获益与治疗成本以达到最大治疗性价比时须考虑到各种放化疗个体化的影响因素,其中包括临床因素与具有广阔发展前景的分子生物学因素.
鼻嚥癌(NPC)對放化療敏感,聯閤放化療可使大多數跼部晚期NPC的生存穫益,但仍有部分患者因聯閤放化療引起的嚴重不良反應而未能達到生存穫益.因此,在權衡治療穫益與治療成本以達到最大治療性價比時鬚攷慮到各種放化療箇體化的影響因素,其中包括臨床因素與具有廣闊髮展前景的分子生物學因素.
비인암(NPC)대방화료민감,연합방화료가사대다수국부만기NPC적생존획익,단잉유부분환자인연합방화료인기적엄중불량반응이미능체도생존획익.인차,재권형치료획익여치료성본이체도최대치료성개비시수고필도각충방화료개체화적영향인소,기중포괄림상인소여구유엄활발전전경적분자생물학인소.
Nasopharyngeal carcinoma (NPC) is sensitive to radiotherapy and chemotherapy.Combined chemoradiotherapy improved the survival of the patients with locally advanced NPC.However,a part of these patients did not gain the survival benefit from the combined chemoradiotherapy because of the additional serious adverse reaction.In order to achieve the best therapeutic gain after balancing the benefit and cost,all kinds of influencing factors of individualized chemoradiotherapy including the clinical and biological molecular factors which has a broad developing prospect must also be considered.