中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2011年
5期
413-414
,共2页
门莉莉%王萍%宋桂荣%邢倩%姚俊洁%杨郁%周海成%杜建玲
門莉莉%王萍%宋桂榮%邢倩%姚俊潔%楊鬱%週海成%杜建玲
문리리%왕평%송계영%형천%요준길%양욱%주해성%두건령
糖尿病,2型%动脉粥样硬化%B-淀粉样肽40%β-淀粉样肽42
糖尿病,2型%動脈粥樣硬化%B-澱粉樣肽40%β-澱粉樣肽42
당뇨병,2형%동맥죽양경화%B-정분양태40%β-정분양태42
Diabetes mellitus,type 2%Atherosclerosis%p-amyloid peptide 40%p-amyloid peptide 42
检测2型糖尿病、动脉粥样硬化(AS)患者血清β-淀粉样肽(Aβ)40和Aβ42水平.结果 显示,Aβ40在糖尿病组高于对照组[(274.70±159.51对162.63±87.58)pg/ml,P<0.05],糖尿病合并AS组升高更显著[(616.95±195.13)pg/ml,P<0.01];单纯AS组Aβ 40水平也明显高于对照组[(318.52±188.65)pg/ml,P<0.05],提示Aβ40是2型糖尿病合并AS的危险因素.而各组间Aβ42水平差异无统计学意义.
檢測2型糖尿病、動脈粥樣硬化(AS)患者血清β-澱粉樣肽(Aβ)40和Aβ42水平.結果 顯示,Aβ40在糖尿病組高于對照組[(274.70±159.51對162.63±87.58)pg/ml,P<0.05],糖尿病閤併AS組升高更顯著[(616.95±195.13)pg/ml,P<0.01];單純AS組Aβ 40水平也明顯高于對照組[(318.52±188.65)pg/ml,P<0.05],提示Aβ40是2型糖尿病閤併AS的危險因素.而各組間Aβ42水平差異無統計學意義.
검측2형당뇨병、동맥죽양경화(AS)환자혈청β-정분양태(Aβ)40화Aβ42수평.결과 현시,Aβ40재당뇨병조고우대조조[(274.70±159.51대162.63±87.58)pg/ml,P<0.05],당뇨병합병AS조승고경현저[(616.95±195.13)pg/ml,P<0.01];단순AS조Aβ 40수평야명현고우대조조[(318.52±188.65)pg/ml,P<0.05],제시Aβ40시2형당뇨병합병AS적위험인소.이각조간Aβ42수평차이무통계학의의.
Serum p-amyloid peptide(Aβ)40 and Ap42 levels in patients with type 2 diabetes mellitus (T2DM)and atherosclerosis(AS)were detected by ELISA.The results showed that serum Ap40 level in T2DM group was significantly higher than that in the control group[(274.70±159.51 vs 162.63±87.58)pg/ml,P<0.05],especially in the diabetic patients accompanied with AS[(616.95±195.13)pg/m],P<0.01].Serum Ap40 level in simple AS group was also higher than that in control group[(318.52± 188.65)pg/ml,P<0.05].These results suggest that Ap40 is a risk factor of T2DM complicated with AS.However,there was no difference in serum Ap42 levels among various groups.
