检验医学
檢驗醫學
검험의학
LABORATORY MEDICINE
2009年
10期
708-710
,共3页
方娴静%郑岚%徐种%傅启华
方嫻靜%鄭嵐%徐種%傅啟華
방한정%정람%서충%부계화
过敏原%体外免疫测试%儿童
過敏原%體外免疫測試%兒童
과민원%체외면역측시%인동
Allergen%In vitro immunity test%Child
目的 研究上海市儿童常见过敏原的致敏情况,为儿童过敏性疾病的防治提供科学依据.方法 应用Mediwiss公司出品的AllergyScreen(敏筛)过敏原检测系统对671例患儿进行常见的吸入性和食入性过敏原体外免疫测试,并计算各种过敏的所占阳性比.结果 吸人性过敏原中以尘螨(粉尘螨和户尘螨)和Mxl点青霉分枝孢子为主,分别占阳性病例的44.75%和26.57%,其中31.23%和6.76%反应级数为3～6级,呈强阳性;其他依次为猫毛皮屑、狗毛皮屑、树花粉组合、蟑螂等.食入性过敏原中以鸡蛋和牛奶为主,分别占阳性病例的34.04%和18.46%,其中5.14%和3.18%反应级数为3～6级,呈强阳性;其他依次为花生、黄豆、腰果,牛肉、羊肉,小麦等.结论 在上海市,粉尘螨、户尘螨和Mxl点青霉分枝孢子是主要的儿童吸人性过敏原,鸡蛋和牛奶是主要的儿童食入性过敏原,总体上儿童食人性过敏原阳性率略高于吸入性过敏原,但反应强度低于吸人性过敏原.开展儿童体外特异性过敏原检测有助于临床诊断过敏性疾病.
目的 研究上海市兒童常見過敏原的緻敏情況,為兒童過敏性疾病的防治提供科學依據.方法 應用Mediwiss公司齣品的AllergyScreen(敏篩)過敏原檢測繫統對671例患兒進行常見的吸入性和食入性過敏原體外免疫測試,併計算各種過敏的所佔暘性比.結果 吸人性過敏原中以塵螨(粉塵螨和戶塵螨)和Mxl點青黴分枝孢子為主,分彆佔暘性病例的44.75%和26.57%,其中31.23%和6.76%反應級數為3～6級,呈彊暘性;其他依次為貓毛皮屑、狗毛皮屑、樹花粉組閤、蟑螂等.食入性過敏原中以鷄蛋和牛奶為主,分彆佔暘性病例的34.04%和18.46%,其中5.14%和3.18%反應級數為3～6級,呈彊暘性;其他依次為花生、黃豆、腰果,牛肉、羊肉,小麥等.結論 在上海市,粉塵螨、戶塵螨和Mxl點青黴分枝孢子是主要的兒童吸人性過敏原,鷄蛋和牛奶是主要的兒童食入性過敏原,總體上兒童食人性過敏原暘性率略高于吸入性過敏原,但反應彊度低于吸人性過敏原.開展兒童體外特異性過敏原檢測有助于臨床診斷過敏性疾病.
목적 연구상해시인동상견과민원적치민정황,위인동과민성질병적방치제공과학의거.방법 응용Mediwiss공사출품적AllergyScreen(민사)과민원검측계통대671례환인진행상견적흡입성화식입성과민원체외면역측시,병계산각충과민적소점양성비.결과 흡인성과민원중이진만(분진만화호진만)화Mxl점청매분지포자위주,분별점양성병례적44.75%화26.57%,기중31.23%화6.76%반응급수위3～6급,정강양성;기타의차위묘모피설、구모피설、수화분조합、장랑등.식입성과민원중이계단화우내위주,분별점양성병례적34.04%화18.46%,기중5.14%화3.18%반응급수위3～6급,정강양성;기타의차위화생、황두、요과,우육、양육,소맥등.결론 재상해시,분진만、호진만화Mxl점청매분지포자시주요적인동흡인성과민원,계단화우내시주요적인동식입성과민원,총체상인동식인성과민원양성솔략고우흡입성과민원,단반응강도저우흡인성과민원.개전인동체외특이성과민원검측유조우림상진단과민성질병.
Objective To investigate common allergens causing children allergic diseases in Shanghai in order to provide a scientific evidence in the preventing and treatment of children allergic diseases. Methods Using automatic in vitro immunity diagnosis meter (AllergySereen), some common kinds of inhalation allergens and food allergens were detected in 671 children allergy cases. The positive rate of each kind of allergen was calculated. Results Dermatophagoides farinae/dermatophagoides pteronyssinus and combination of Streptomyces were the main inhalation allergens and the positive rates of them were 44.75% and 26.57%, respectively, which 31.23% and 6.76% were 3-6 reaction order, and the rates showed strong positive. Other common allergens were cat's and dog's hair, combination of tree/flower's farina and cockroaches. The main food allergens were eggs and milk and the positive rates of them were 34.04% and 18.46%, respectively, which 5.14% and 3.18% were 3-6 reaction order, and the rates showed strong positive. Other common food allergens were peanut, soybean, cashew, beef, mutton and wheat. Conclusions In Shanghai, dermatophagoides farinae, dermatophagoides pteronyssinus and combination of Straptomyces are the main inhalation allergens and eggs and milk are the main food allergens for children. As a whole, the positive rate of food allergens in children with allergy diseases is higher than that of inhalation allergens, however, the former intensity of reaction is lower than that of inhalation allergens. In vitro detection of specific allergens can help the clinical diagnosis of allergic diseases.
