国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2010年
3期
191-192,后插1-后插2
,共3页
间质干细胞%血脑屏障%通透性%体外模型
間質榦細胞%血腦屏障%通透性%體外模型
간질간세포%혈뇌병장%통투성%체외모형
Mesenchymal stem cells%Blood-brain barrier%Permeability%Vitro model
间质干细胞可通过脑实质、血液和脑脊液等移植方式进入脑组织,修复损伤组织,促进神经功能恢复,是治疗中枢神经系统疾病的理想种子细胞;但血脑屏障存在着特殊结构,研究间质干细胞与血脑屏障通透性的相关性,使更多间质干细胞穿过血脑屏障.综述了间质干细胞与血脑屏障通透性的最新研究进展.
間質榦細胞可通過腦實質、血液和腦脊液等移植方式進入腦組織,脩複損傷組織,促進神經功能恢複,是治療中樞神經繫統疾病的理想種子細胞;但血腦屏障存在著特殊結構,研究間質榦細胞與血腦屏障通透性的相關性,使更多間質榦細胞穿過血腦屏障.綜述瞭間質榦細胞與血腦屏障通透性的最新研究進展.
간질간세포가통과뇌실질、혈액화뇌척액등이식방식진입뇌조직,수복손상조직,촉진신경공능회복,시치료중추신경계통질병적이상충자세포;단혈뇌병장존재착특수결구,연구간질간세포여혈뇌병장통투성적상관성,사경다간질간세포천과혈뇌병장.종술료간질간세포여혈뇌병장통투성적최신연구진전.
Mesenchymal stem cells(MSCs), which can be introduced in brain tissue by the strategies of brain parenchyma, blood and neurolymph transplantation, to repair tissue injury and promote functional recovery of neural system, have been considered as the ideal seed cells for the treatment of central nervous system diseases. However, as the special structure exists in the blood-brain barrier, study on correlation between MSCs and blood-brain barrier permeability will make it possible for more MSCs to pass the barrier to perform the treatment. This paper gives a review on the latest research development in the field.