国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
13期
978-980
,共3页
慢性阻塞性肺疾病%肺功能测试%支气管舒张试验
慢性阻塞性肺疾病%肺功能測試%支氣管舒張試驗
만성조새성폐질병%폐공능측시%지기관서장시험
Chronic obstructive pulmonary disease%Pulmonary function testing%Bronchial diastolic test
目的 探讨不同严重程度的慢性阻塞性肺疾病( COPD)患者对支气管舒张试验的反应性差异.方法 入选Ⅰ～Ⅳ级COPD稳定期患者共411例,采用支气管舒张试验比较支气管舒张前后第1秒用力呼气容积(FEV1)、用力肺活量(FVC)和深吸气量(IC)的改变值和改变率.结果 支气管舒张试验后,COPD患者的FEV1、FVC和IC均有增加,比试验前差异有统计学意义(P＜0.01).随着COPD严重程度的增加,FEV1的改变值逐渐减少,而FVC和IC改变值却逐渐增加.结论 随着COPD的严重程度加重,吸入支气管舒张剂后,FVC和IC改变值越大,FVC和IC是重度COPD患者对支气管舒张剂反应性的指标.
目的 探討不同嚴重程度的慢性阻塞性肺疾病( COPD)患者對支氣管舒張試驗的反應性差異.方法 入選Ⅰ～Ⅳ級COPD穩定期患者共411例,採用支氣管舒張試驗比較支氣管舒張前後第1秒用力呼氣容積(FEV1)、用力肺活量(FVC)和深吸氣量(IC)的改變值和改變率.結果 支氣管舒張試驗後,COPD患者的FEV1、FVC和IC均有增加,比試驗前差異有統計學意義(P＜0.01).隨著COPD嚴重程度的增加,FEV1的改變值逐漸減少,而FVC和IC改變值卻逐漸增加.結論 隨著COPD的嚴重程度加重,吸入支氣管舒張劑後,FVC和IC改變值越大,FVC和IC是重度COPD患者對支氣管舒張劑反應性的指標.
목적 탐토불동엄중정도적만성조새성폐질병( COPD)환자대지기관서장시험적반응성차이.방법 입선Ⅰ～Ⅳ급COPD은정기환자공411례,채용지기관서장시험비교지기관서장전후제1초용력호기용적(FEV1)、용력폐활량(FVC)화심흡기량(IC)적개변치화개변솔.결과 지기관서장시험후,COPD환자적FEV1、FVC화IC균유증가,비시험전차이유통계학의의(P＜0.01).수착COPD엄중정도적증가,FEV1적개변치축점감소,이FVC화IC개변치각축점증가.결론 수착COPD적엄중정도가중,흡입지기관서장제후,FVC화IC개변치월대,FVC화IC시중도COPD환자대지기관서장제반응성적지표.
Objective Evaluated the difference of lung volume response to bronchodilators in patients with different severity chronic obstructive pulmonary disease (COPD).Methods 411 patients with COPD were enrolled in this study.The severity of COPD was graded according to the GOLD criteria.The change of FEV1,FVC and IC 20 minutes after inhalation of salbutamol 400 μg via spacer were measuered and compared.Results The values of FEV1,FVC and IC were significantly increased after inhalation of salbutamol ( P ＜ 0.01).The improvement of FEV1 decreased as a function of the severity of COPD.In contrast,the improvement of FVC and IC were increased in those with more severe disease.Conclusions The improvement of FVC and IC is increased in patients with more severe COPD.The reversibility of COPD should be evaluated by FVC and IC.
