国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2012年
7期
601-605
,共5页
冠心病介入术后再狭窄%益气养阴、活血通脉法
冠心病介入術後再狹窄%益氣養陰、活血通脈法
관심병개입술후재협착%익기양음、활혈통맥법
Restenosis after percutaneous coronary intervention%Method of reinforcing qinourishing yin and promoting blood circulation to remove blood stasis
目的 观察益气养阴、活血通脉法治疗冠心病介入术后再狭窄的临床疗效.方法 选择2008年10月至2011年5月我院内科门诊冠心病介入术后再狭窄患者,采用随机数字表法分为两组各30例.对照组予常规西药治疗,治疗组在常规西药治疗的基础上加用益气养阴、活血通脉的中药,疗程6个月.观察患者临床症状、冠状动脉CT血管造影(CTA)、血脂等的变化.结果 治疗组总有效率为93.33％,对照组为66.67％,两组总有效率比较,差异有统计学意义(x2=8.787,P＜0.05).治疗组治疗后胸痛、胸闷、气短、乏力、口干的症状积分得到明显改善[分别为( 1.07±1.01)分、(1.33±1.21)分、(1.47±1.17)分、(1.53±1.14)分、(1.53±1.01)分,(P＜0.05)],且优于对照组[分别为(2.07±1.53)分、(2.27±1.46)分、(3.73±1.46)分、(3.73±1.87)分、(3.13±1.63)分,(P＜0.05)].冠状动脉造影或冠状动脉CTA的结果显示,治疗组患者再狭窄的程度均未见加重或出现新的再狭窄.治疗组治疗后胆固醇(CHOL)、甘油三酯(TG)、高密度脂蛋白胆固醇( HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平[分别为(4.55±0.44)mmol/L、(1.81±0.56)mmol/L、(1.26±0.38) mmol/L、(2.25±0.49) mmol/L,(P＜0.05)]均较疗前明显改善,且优于对照组治疗后CHOL、TG、LDL-C[分别为(4.86±0.63) mmol/L、(2.29±1.06) mmol/L、(2.60±0.73) mmol/L,(P＜0.05)]的水平.结论 益气养阴、活血通脉法可改善患者的临床症状和血脂水平,对防治介入术后再狭窄有一定的作用.
目的 觀察益氣養陰、活血通脈法治療冠心病介入術後再狹窄的臨床療效.方法 選擇2008年10月至2011年5月我院內科門診冠心病介入術後再狹窄患者,採用隨機數字錶法分為兩組各30例.對照組予常規西藥治療,治療組在常規西藥治療的基礎上加用益氣養陰、活血通脈的中藥,療程6箇月.觀察患者臨床癥狀、冠狀動脈CT血管造影(CTA)、血脂等的變化.結果 治療組總有效率為93.33％,對照組為66.67％,兩組總有效率比較,差異有統計學意義(x2=8.787,P＜0.05).治療組治療後胸痛、胸悶、氣短、乏力、口榦的癥狀積分得到明顯改善[分彆為( 1.07±1.01)分、(1.33±1.21)分、(1.47±1.17)分、(1.53±1.14)分、(1.53±1.01)分,(P＜0.05)],且優于對照組[分彆為(2.07±1.53)分、(2.27±1.46)分、(3.73±1.46)分、(3.73±1.87)分、(3.13±1.63)分,(P＜0.05)].冠狀動脈造影或冠狀動脈CTA的結果顯示,治療組患者再狹窄的程度均未見加重或齣現新的再狹窄.治療組治療後膽固醇(CHOL)、甘油三酯(TG)、高密度脂蛋白膽固醇( HDL-C)、低密度脂蛋白膽固醇(LDL-C)水平[分彆為(4.55±0.44)mmol/L、(1.81±0.56)mmol/L、(1.26±0.38) mmol/L、(2.25±0.49) mmol/L,(P＜0.05)]均較療前明顯改善,且優于對照組治療後CHOL、TG、LDL-C[分彆為(4.86±0.63) mmol/L、(2.29±1.06) mmol/L、(2.60±0.73) mmol/L,(P＜0.05)]的水平.結論 益氣養陰、活血通脈法可改善患者的臨床癥狀和血脂水平,對防治介入術後再狹窄有一定的作用.
목적 관찰익기양음、활혈통맥법치료관심병개입술후재협착적림상료효.방법 선택2008년10월지2011년5월아원내과문진관심병개입술후재협착환자,채용수궤수자표법분위량조각30례.대조조여상규서약치료,치료조재상규서약치료적기출상가용익기양음、활혈통맥적중약,료정6개월.관찰환자림상증상、관상동맥CT혈관조영(CTA)、혈지등적변화.결과 치료조총유효솔위93.33％,대조조위66.67％,량조총유효솔비교,차이유통계학의의(x2=8.787,P＜0.05).치료조치료후흉통、흉민、기단、핍력、구간적증상적분득도명현개선[분별위( 1.07±1.01)분、(1.33±1.21)분、(1.47±1.17)분、(1.53±1.14)분、(1.53±1.01)분,(P＜0.05)],차우우대조조[분별위(2.07±1.53)분、(2.27±1.46)분、(3.73±1.46)분、(3.73±1.87)분、(3.13±1.63)분,(P＜0.05)].관상동맥조영혹관상동맥CTA적결과현시,치료조환자재협착적정도균미견가중혹출현신적재협착.치료조치료후담고순(CHOL)、감유삼지(TG)、고밀도지단백담고순( HDL-C)、저밀도지단백담고순(LDL-C)수평[분별위(4.55±0.44)mmol/L、(1.81±0.56)mmol/L、(1.26±0.38) mmol/L、(2.25±0.49) mmol/L,(P＜0.05)]균교료전명현개선,차우우대조조치료후CHOL、TG、LDL-C[분별위(4.86±0.63) mmol/L、(2.29±1.06) mmol/L、(2.60±0.73) mmol/L,(P＜0.05)]적수평.결론 익기양음、활혈통맥법가개선환자적림상증상화혈지수평,대방치개입술후재협착유일정적작용.
Objective To observe the clinical effects of the method of reinforcing qi,nourish ing yin and promoting blood circulation to remove blood stasis in the treatment of restenosis after percutaneous coronary intervention.Methods 60 coronary heart disease patients who had accepted PCI treatment and occurred restenosis were randomly recruited into a control group and a treatment group,30 eases in each group.The control group received conventional therapy.The treatment group was treated with conventional therapy combined with TCM of reinforcing qi,nourishing yin and promoting blood circulation to remove blood stasis.Both groups were treated for 6 months.The clinical symptoms,coronary angiography or coronary artery CTA,blood lipids were observed.Results The total effective rate was 93.33％ and 66.67％ in the treatment group and the control group respectively,showing statistical difference (x2=8.787,P＜0.05).The patients' clinical symptoms in the treatment group were improved,such as chest pain,chest tightness,shortness of breath,fatigue,dry mouth [The scores were respectively(1.07± 1.01)、(1.33±1.21)、(1.47±1.17)、(1.53±1.14)、(1.53± 1.01),(P＜0.05) ].The treatment group demonstrated a significantly better therapeutic results than the control group [Thescoreswererespectively(2.07±1.53)、(2.27±1.46)、(3.73±1.46)、(3.73±1.87)、(3.13±1.63),(P＜0.05) ].The results of coronary angiography or coronary artery CTA showed that the narrow degree in the treatment group was no more aggravating and it had no new restenosis.After the treatment,the level of CHOL、TG、HDL-C、LDL-C in the treatment group was improved [They were respectively (4.55±0.44)mmol/L、(1.81±0.56)mmol/L、(1.26±0.38)mmol/L、(2.25±0.49)mmol/L,(P＜0.05) ].The improvement in CHOL、TG、LDL-C of the treatment group was better than that of the control group [They were respectively (4.86±0.63)mmol/L、(2.29±1.06)mmol/L,(2.60±0.73)mmol/L,(P＜0.05)].Conclusion The method of reinforcing qi,nourishing yin and promoting blood circulation to remove blood stasis could improve the patients clinical symptoms and blood lipids,and therefore spreventing restenosis.
