中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2011年
z1期
39-41
,共3页
急性脑梗死%脂联素%同型半胱氨酸%C反应蛋白
急性腦梗死%脂聯素%同型半胱氨痠%C反應蛋白
급성뇌경사%지련소%동형반광안산%C반응단백
Acute cerebral infarction%Adiponectin%Homocysteine%CRP
目的 观察急性脑梗死患者血清脂联素与CRP和Hcy的相关性,进一步探讨其发病机制.方法 测定80例急性脑梗死患者(脑梗死组)和80例健康者(对照组)的血清脂联素、hs-CRP、Hcy、血脂、FPG和血压等指标.结果 急性脑梗死患者的血清hs-CRP、Hcy、TG和收缩压显著高于对照组(P＜0.05),血清脂联素显著低于对照组(P＜0.05).脂联素与Hcy(r=-0.453)、hs-CRP(r=-0.397)、TG(r=-0.321)、FPG(r=-0.318)和收缩压(r=-0.288)呈负相关(P＜0.05).结论 脂联素与Hcy和hs-CRP、糖脂代谢和血压相互影响,共同参与急性脑梗死发生发展的病理生理过程.
目的 觀察急性腦梗死患者血清脂聯素與CRP和Hcy的相關性,進一步探討其髮病機製.方法 測定80例急性腦梗死患者(腦梗死組)和80例健康者(對照組)的血清脂聯素、hs-CRP、Hcy、血脂、FPG和血壓等指標.結果 急性腦梗死患者的血清hs-CRP、Hcy、TG和收縮壓顯著高于對照組(P＜0.05),血清脂聯素顯著低于對照組(P＜0.05).脂聯素與Hcy(r=-0.453)、hs-CRP(r=-0.397)、TG(r=-0.321)、FPG(r=-0.318)和收縮壓(r=-0.288)呈負相關(P＜0.05).結論 脂聯素與Hcy和hs-CRP、糖脂代謝和血壓相互影響,共同參與急性腦梗死髮生髮展的病理生理過程.
목적 관찰급성뇌경사환자혈청지련소여CRP화Hcy적상관성,진일보탐토기발병궤제.방법 측정80례급성뇌경사환자(뇌경사조)화80례건강자(대조조)적혈청지련소、hs-CRP、Hcy、혈지、FPG화혈압등지표.결과 급성뇌경사환자적혈청hs-CRP、Hcy、TG화수축압현저고우대조조(P＜0.05),혈청지련소현저저우대조조(P＜0.05).지련소여Hcy(r=-0.453)、hs-CRP(r=-0.397)、TG(r=-0.321)、FPG(r=-0.318)화수축압(r=-0.288)정부상관(P＜0.05).결론 지련소여Hcy화hs-CRP、당지대사화혈압상호영향,공동삼여급성뇌경사발생발전적병리생리과정.
Objective To investigate the correlation between adiponectin, CRP and homocysteine (Hcy) and evaluate its mechanism in acute cerebral infarction. Methods Serum adiponectin, hs-CRP,Hcy, blood lipid, FPG and blood pressure were measured in eighty patients with acute cerebral infarction ( cerebral infarction group) and eighty healthy persons ( control group). Results In cerebral infarction group, serum hs-CRP, Hcy, TG , and systolic pressure were significantly higher than in control group ( P ＜0. 05) , while serum adiponectin were significantly lower than in control group ( P ＜0. 05). Serum adiponectin levels were negatively correlated with Hcy( r = -0. 453) , hs-CRP ( r = -0. 397) ,TG( r = -0. 321) , FPG( r = -0. 318) and systolic pressure ( r = -0. 288). Conclusion There is correlation between adiponectin, Hcy, hs-CRP, glucose and lipid metabolism and blood pressure, which plays a role in occurrenc and development of acute cerebral infarction.
