中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
23期
45-47
,共3页
刘林%王庆本%袁义波%马友田
劉林%王慶本%袁義波%馬友田
류림%왕경본%원의파%마우전
盐酸戊乙奎醚%腰硬联合麻醉%剖宫产
鹽痠戊乙奎醚%腰硬聯閤痳醉%剖宮產
염산무을규미%요경연합마취%부궁산
Penehyclidine hydrochloride%Combined spinal and epidural anesthesia%Caesarean section
目的 观察盐酸戊乙奎醚对腰硬联合麻醉下剖宫产产妇及胎儿的影响.方法 60例择期剖宫产手术患者随机分为两组:A组为盐酸戊乙奎醚组;B组为东莨菪碱组,每组30例.术前30 min,A组肌肉注射盐酸戊乙奎醚0.5 mg,B组肌肉注射东莨菪碱0.5 mg,记录用药前,麻醉前,麻醉后3、5、10 min及术毕时的收缩压、舒张压、心率,同时观察术中寒战的发生率并记录胎儿娩出后1 min和5 min的Apgar评分.结果 与用药前相比,A组心率麻醉前有所减慢,但差异无统计学意义,其他各时点无明显变化;B组心率在麻醉后3、5、10 min明显增快,差异有统计学意义(P＜0.05).组间比较,两组间HR差异有统计学意义.与用药前相比,两组麻醉后收缩压和舒张压均有所降低,在麻醉后3 ～ 10 min明显,差异有统计学意义,但均在正常范围之内;组间比较差异无统计学意义.两组间Apgar评分比较无统计学意义.与B组相比,A组寒战发生率较低,差异有统计学意义(P＜0.05).结论 盐酸戊乙奎醚可安全用于剖宫产产妇的术前用药,并显著降低寒战的发生率,对新生儿无不良影响,适合临床推广应用.
目的 觀察鹽痠戊乙奎醚對腰硬聯閤痳醉下剖宮產產婦及胎兒的影響.方法 60例擇期剖宮產手術患者隨機分為兩組:A組為鹽痠戊乙奎醚組;B組為東莨菪堿組,每組30例.術前30 min,A組肌肉註射鹽痠戊乙奎醚0.5 mg,B組肌肉註射東莨菪堿0.5 mg,記錄用藥前,痳醉前,痳醉後3、5、10 min及術畢時的收縮壓、舒張壓、心率,同時觀察術中寒戰的髮生率併記錄胎兒娩齣後1 min和5 min的Apgar評分.結果 與用藥前相比,A組心率痳醉前有所減慢,但差異無統計學意義,其他各時點無明顯變化;B組心率在痳醉後3、5、10 min明顯增快,差異有統計學意義(P＜0.05).組間比較,兩組間HR差異有統計學意義.與用藥前相比,兩組痳醉後收縮壓和舒張壓均有所降低,在痳醉後3 ～ 10 min明顯,差異有統計學意義,但均在正常範圍之內;組間比較差異無統計學意義.兩組間Apgar評分比較無統計學意義.與B組相比,A組寒戰髮生率較低,差異有統計學意義(P＜0.05).結論 鹽痠戊乙奎醚可安全用于剖宮產產婦的術前用藥,併顯著降低寒戰的髮生率,對新生兒無不良影響,適閤臨床推廣應用.
목적 관찰염산무을규미대요경연합마취하부궁산산부급태인적영향.방법 60례택기부궁산수술환자수궤분위량조:A조위염산무을규미조;B조위동랑탕감조,매조30례.술전30 min,A조기육주사염산무을규미0.5 mg,B조기육주사동랑탕감0.5 mg,기록용약전,마취전,마취후3、5、10 min급술필시적수축압、서장압、심솔,동시관찰술중한전적발생솔병기록태인면출후1 min화5 min적Apgar평분.결과 여용약전상비,A조심솔마취전유소감만,단차이무통계학의의,기타각시점무명현변화;B조심솔재마취후3、5、10 min명현증쾌,차이유통계학의의(P＜0.05).조간비교,량조간HR차이유통계학의의.여용약전상비,량조마취후수축압화서장압균유소강저,재마취후3 ～ 10 min명현,차이유통계학의의,단균재정상범위지내;조간비교차이무통계학의의.량조간Apgar평분비교무통계학의의.여B조상비,A조한전발생솔교저,차이유통계학의의(P＜0.05).결론 염산무을규미가안전용우부궁산산부적술전용약,병현저강저한전적발생솔,대신생인무불량영향,괄합림상추엄응용.
Objective To observe the effect of penehyclidine hydrochloride on parturient and fetus in caesarean section under combined spinal and epidural anesthesia.Methods Sixty patients scheduled for cesarean section were randomly divided into two groups with 30 patients in each group:the penehyclidine hydrochloride(group A)and the scopolamine(group B).Then the SBP,DBP,HR were observed and recorded before anesthesia and postanesthetic time interval.And the incidence rate of shivering,neonatal Apgar score at 1 min and 5 min were recorded.Results Compared with before using drugs,the HR of group A was slower before anesthesia but there was no significant difference.There was no obvious change at the other time.The HR of group B was significant increased at 3 min,5 min and 10 min after anesthesia.The HR of the two groups had statistical significance.The SBP and DBP of the two groups was lower after anesthesia,especially during 3-10 min.But there was no significant difference between the two groups in BP and Apgar score.Compared with group B,the incidence rate of shivering was lower than that of group A.Conclusions Penehyclidine hydrochloride could be used in parturient safely as premedication,and can reduce the incidence rate of shivering significantly,but had no side effects on fetus,and deserves further clinical aPPlications.
