中国血吸虫病防治杂志
中國血吸蟲病防治雜誌
중국혈흡충병방치잡지
CHINESE JOURNAL OF SCHISTOSOMIASIS CONTROL
2010年
2期
171-173
,共3页
张世微%程斌%渠洪捷%陈仲民%邹琴%褚丽平%张琳%何焕然%汤胜华%黄小平%杨红梅
張世微%程斌%渠洪捷%陳仲民%鄒琴%褚麗平%張琳%何煥然%湯勝華%黃小平%楊紅梅
장세미%정빈%거홍첩%진중민%추금%저려평%장림%하환연%탕성화%황소평%양홍매
血吸虫病%筛查%效度%胶体染料试纸条法%低度流行区
血吸蟲病%篩查%效度%膠體染料試紙條法%低度流行區
혈흡충병%사사%효도%효체염료시지조법%저도류행구
Schistosomiasis%Screening%Validity%Dipstick dye immuno-assay (DDIA)%Lower endemic area
目的 探索胶体染料试纸条法(DDIA)在孝感市血吸虫病低度流行区的应用价值.方法 在孝感市低度流行区随机选择一自然村,对6～65岁村民同时采用粪便集卵孵化法、DDIA、IHA、ELISA和询检筛查同一群体,以粪便集卵孵化法为标准,评价其他几种方法的效度,并比较其费用.结果 共筛查287人,粪检、IHA、DDIA、ELISA及询检阳性率分别为1.74%、7.67%、9.06%、19.51%、29.97%.以粪检为金标准,IHA、DDIA、ELISA及询检约登指数分别为0.74、0.72、0.62、0.30,符合率分别为93.38%、91.99%、81.53%、70.03%,上述方法筛查1例病人所需费用分别为16.70、4.95、4.12、5.63、2.44元.结论 DDIA用于低度流行区血吸虫病筛查效度较好,且操作简便、费用经济,可用于大规模筛查.
目的 探索膠體染料試紙條法(DDIA)在孝感市血吸蟲病低度流行區的應用價值.方法 在孝感市低度流行區隨機選擇一自然村,對6～65歲村民同時採用糞便集卵孵化法、DDIA、IHA、ELISA和詢檢篩查同一群體,以糞便集卵孵化法為標準,評價其他幾種方法的效度,併比較其費用.結果 共篩查287人,糞檢、IHA、DDIA、ELISA及詢檢暘性率分彆為1.74%、7.67%、9.06%、19.51%、29.97%.以糞檢為金標準,IHA、DDIA、ELISA及詢檢約登指數分彆為0.74、0.72、0.62、0.30,符閤率分彆為93.38%、91.99%、81.53%、70.03%,上述方法篩查1例病人所需費用分彆為16.70、4.95、4.12、5.63、2.44元.結論 DDIA用于低度流行區血吸蟲病篩查效度較好,且操作簡便、費用經濟,可用于大規模篩查.
목적 탐색효체염료시지조법(DDIA)재효감시혈흡충병저도류행구적응용개치.방법 재효감시저도류행구수궤선택일자연촌,대6～65세촌민동시채용분편집란부화법、DDIA、IHA、ELISA화순검사사동일군체,이분편집란부화법위표준,평개기타궤충방법적효도,병비교기비용.결과 공사사287인,분검、IHA、DDIA、ELISA급순검양성솔분별위1.74%、7.67%、9.06%、19.51%、29.97%.이분검위금표준,IHA、DDIA、ELISA급순검약등지수분별위0.74、0.72、0.62、0.30,부합솔분별위93.38%、91.99%、81.53%、70.03%,상술방법사사1례병인소수비용분별위16.70、4.95、4.12、5.63、2.44원.결론 DDIA용우저도류행구혈흡충병사사효도교호,차조작간편、비용경제,가용우대규모사사.
Objective To explore the application value of dipstick dye immuno-assay (DDIA) for screening the schistosomiasis chemotherapy targets in the low endemic areas of Xiaogan City.Methods The residents aged 6-65 years in a village in the low endemic areas of schistosomiasis of Xiaogan City were selected and tested by the methods of fecal examination,DDIA,indirect hemagghitination (IHA),enzyme linked immunosorbent assay (ELISA) and inquiry,and the results of fecal examination were determined as the gold standard.Results The Youden' s indices of IHA,DDIA,ELISA and inquiry were 0.74,0.72,0.62 and 0.30,respectively,and the consistency rates of them were 93.38%,91.99%,81.53% and 70.03%,respectively.It took 16.70,4.95,4.12,5.63 and 2.44 Yuan screening one patient with the fecal examination,IHA,DDIA,ELISA and inquiry,respectively.Conclusion The validity of DDIA with simple operation and low cost for screening the schistosomiasis chemotherapy targets is satisfying,and the method is suitable for large scale screening in low endemic areas.
