国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
4期
513-516
,共4页
容永忠%李斌%梁敬德%陈俏仪%范雪莲
容永忠%李斌%樑敬德%陳俏儀%範雪蓮
용영충%리빈%량경덕%진초의%범설련
C反应蛋白%白细胞%儿科%感染性疾病
C反應蛋白%白細胞%兒科%感染性疾病
C반응단백%백세포%인과%감염성질병
C-reactive protein%WBC%Paediatrics%Infectious disease
目的 探讨C反应蛋白(CRP)在儿科感染性疾病早期诊断和鉴别诊断中的应用价值.方法 选择临床确诊为细菌感染的患儿45例(细菌感染组)、病毒感染的患儿41例(病毒感染组)和健康儿童40名(对照组),分别在入院时和抗感染治疗72h后采用HITACHI7060全自动生化分析仪检测其CRP含量、采用东亚KX-21血球计数仪进行WBC计数,并对结果进行统计学分析处理.结果 细菌感染组患儿CRP水平(57.2±19.5)mg/L和WBC计数(18.6±8.3)×109/L均明显高于病毒感染组的(5.9±3.2) mg/L、(7.9±4.4)×109/L和正常对照组的(5.2±1.7) mg/L、(7.7±2.5)×109/L,P均＜0.05；细菌感染组患儿CRP的阳性率(86.7％)明显高于WBC的阳性率(71.1％),P＜ 0.01,且其CRP和WBC的阳性率均明显高于病毒感染组(9.8％,12.2％),P均＜0.001.细菌感染组患儿经抗感染治疗72 h后CRP水平为(5.8±4.5) mg/L,基本恢复正常,WBC计数下降幅度则不大,至(12.9±7.1)×109/L (P＜ 0.01).结论 CRP检测有助于儿科感染性疾病的早期诊断,对于细菌感染和病毒感染的鉴别诊断具有重要价值.
目的 探討C反應蛋白(CRP)在兒科感染性疾病早期診斷和鑒彆診斷中的應用價值.方法 選擇臨床確診為細菌感染的患兒45例(細菌感染組)、病毒感染的患兒41例(病毒感染組)和健康兒童40名(對照組),分彆在入院時和抗感染治療72h後採用HITACHI7060全自動生化分析儀檢測其CRP含量、採用東亞KX-21血毬計數儀進行WBC計數,併對結果進行統計學分析處理.結果 細菌感染組患兒CRP水平(57.2±19.5)mg/L和WBC計數(18.6±8.3)×109/L均明顯高于病毒感染組的(5.9±3.2) mg/L、(7.9±4.4)×109/L和正常對照組的(5.2±1.7) mg/L、(7.7±2.5)×109/L,P均＜0.05；細菌感染組患兒CRP的暘性率(86.7％)明顯高于WBC的暘性率(71.1％),P＜ 0.01,且其CRP和WBC的暘性率均明顯高于病毒感染組(9.8％,12.2％),P均＜0.001.細菌感染組患兒經抗感染治療72 h後CRP水平為(5.8±4.5) mg/L,基本恢複正常,WBC計數下降幅度則不大,至(12.9±7.1)×109/L (P＜ 0.01).結論 CRP檢測有助于兒科感染性疾病的早期診斷,對于細菌感染和病毒感染的鑒彆診斷具有重要價值.
목적 탐토C반응단백(CRP)재인과감염성질병조기진단화감별진단중적응용개치.방법 선택림상학진위세균감염적환인45례(세균감염조)、병독감염적환인41례(병독감염조)화건강인동40명(대조조),분별재입원시화항감염치료72h후채용HITACHI7060전자동생화분석의검측기CRP함량、채용동아KX-21혈구계수의진행WBC계수,병대결과진행통계학분석처리.결과 세균감염조환인CRP수평(57.2±19.5)mg/L화WBC계수(18.6±8.3)×109/L균명현고우병독감염조적(5.9±3.2) mg/L、(7.9±4.4)×109/L화정상대조조적(5.2±1.7) mg/L、(7.7±2.5)×109/L,P균＜0.05；세균감염조환인CRP적양성솔(86.7％)명현고우WBC적양성솔(71.1％),P＜ 0.01,차기CRP화WBC적양성솔균명현고우병독감염조(9.8％,12.2％),P균＜0.001.세균감염조환인경항감염치료72 h후CRP수평위(5.8±4.5) mg/L,기본회복정상,WBC계수하강폭도칙불대,지(12.9±7.1)×109/L (P＜ 0.01).결론 CRP검측유조우인과감염성질병적조기진단,대우세균감염화병독감염적감별진단구유중요개치.
Objective To study the application value of C-reactive protein in the early diagnosis and differential diagnosis for paediatrics infectious disease.Methods 45 paediatrics patients with bacterial infection,41 paediatrics patients with virus infection and 40 healthy children were divided into the bacterial infection group,the virus infection group and the health children group(control group) respectively.The levels of CRP were detected by HITACHI7180 automatic biochemistry analyzer and the WBC was counted by SystemKX-21 automatic blood analysis instrument differently when they came to hospital and had been treated with antiinfective for 72 hours.And the statistic study was made to evaluate the results.Results The levels of CRP ( 57.2 ± 19.5 mg/L ) and WBC count ( 18.6 ± 8.3 × 109/L ) of the bacterial infection group were also significantly higher than those of the virus infection group ( 5.9 ± 3.2mg/L,7.9 ± 4.4 × 109/L ) and the control group ( 5.2 ± 1.7 mg/L,7.7 ± 2.5 × 109/L)(P ＜ 0.05).The positive rate of C RP ( 86.7％ )was significantly higher than that of WBC in the bacterial infection group ( 71.1％)(P＜ 0.01),and the positive rates of CRP and WBC were also significantly higher than those of the virus infection group ( 9.8％,12.2％)(P＜ 0.01).The levels of CRP of the bacterial infection group returned to the normal level (5.8 ± 4.5 mg/L) when they had been treated with antiinfective for 72 hours,but WBC did not decrease much (12.9 ± 7.1 × 109/L) (P ＜ 0.01).Condusion:CRP is helpful to the early diagnosis of paediatrics infectious disease and differentiating bacterial infection from viral infection.
