国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2009年
6期
428-430
,共3页
放射疗法%头颈部肿瘤%甲状腺功能减退症
放射療法%頭頸部腫瘤%甲狀腺功能減退癥
방사요법%두경부종류%갑상선공능감퇴증
Radiotherapy%Head and neck neoplasms%Hypothyroidism
头颈部肿瘤放疗后会引起不同程度的甲状腺功能减退.引起甲状腺功能减退的机制包括射线对甲状腺及垂体细胞的直接损伤、对相关血管的损伤以及自身免疫反应等.影响头颈部肿瘤放疗后甲状腺功能的因素主要有:放疗剂量、放疗技术、是否联合手术化疗等.通过对这些影响因素的研究可为防治甲状腺功能减退提供依据,从而提高患者生活质量.
頭頸部腫瘤放療後會引起不同程度的甲狀腺功能減退.引起甲狀腺功能減退的機製包括射線對甲狀腺及垂體細胞的直接損傷、對相關血管的損傷以及自身免疫反應等.影響頭頸部腫瘤放療後甲狀腺功能的因素主要有:放療劑量、放療技術、是否聯閤手術化療等.通過對這些影響因素的研究可為防治甲狀腺功能減退提供依據,從而提高患者生活質量.
두경부종류방료후회인기불동정도적갑상선공능감퇴.인기갑상선공능감퇴적궤제포괄사선대갑상선급수체세포적직접손상、대상관혈관적손상이급자신면역반응등.영향두경부종류방료후갑상선공능적인소주요유:방료제량、방료기술、시부연합수술화료등.통과대저사영향인소적연구가위방치갑상선공능감퇴제공의거,종이제고환자생활질량.
Thyroid dysfunction, referred as hypothyroidism, is one of the sequelaes in head and neck cancer patients treated by radiotherapy. The mechanisms of hypothyroidism induced by radiotherapy include direct damage of the thyroid and/or pituitary cells, involved blood vessels damage, as well as autoimmune response. Factors related to postirradiation thyroid dysfunction are diverse, including radiation dose, technique, whether or not in combination with surgery and/or chemotherapy. In addition, age, sex and race may also contrib-ute as impact factors. Further investigation of these factors can provide for prevention and treatment of hypothyroidism, and improve patients life quality.
