CAJ | 학술논문

目的探讨18F-FDG PET-CT显像诊断非小细胞肺癌(NSCLC)的价值.方法对2004年2月至2005年5月91例NSCLC和10例肺良性病变患者的PET-CT检查结果、临床诊断和治疗资料进行分析.结果 91例NSCLC病灶标准摄取值(SUV)均阳性,PET-CT均能正确诊断.10例肺良性病变,SUV阳性3例,包括结核2例和炎性假瘤1例,SUV阴性7例.PET-CT正确诊断9例,1例结核患者PET-CT误诊为肺癌.PET-CT显像诊断NSCLC的敏感性、特异性和准确性分别为100%、90%和99%.91例NSCLC根治手术治疗48例.纵隔淋巴结转移30例,PET-CT正确诊断28例,假阴性2例.纵隔淋巴结无转移18例,PET-CT正确诊断17例,假阳性1例.PET-CT显像诊断NSCLC纵隔淋巴结转移的敏感性、特异性和准确性分别为93.3%、94.4%和93.8%.远处转移33例,PET-CT均能正确诊断.结论 PET-CT显像融合了功能代谢和图像解剖,对肺原发灶和其他脏器的转移能作出正确的诊断.对NSCLC诊断的准确性达90%以上.
목적 탐토18F-FDG PET-CT현상진단비소세포폐암(NSCLC)적개치.방법 대2004년2월지2005년5월91례NSCLC화10례폐량성병변환자적PET-CT검사결과、림상진단화치료자료진행분석.결과 91례NSCLC병조표준섭취치(SUV)균양성,PET-CT균능정학진단.10례폐량성병변,SUV양성3례,포괄결핵2례화염성가류1례,SUV음성7례.PET-CT정학진단9례,1례결핵환자PET-CT오진위폐암.PET-CT현상진단NSCLC적민감성、특이성화준학성분별위100%、90%화99%.91례NSCLC근치수술치료48례.종격림파결전이30례,PET-CT정학진단28례,가음성2례.종격림파결무전이18례,PET-CT정학진단17례,가양성1례.PET-CT현상진단NSCLC종격림파결전이적민감성、특이성화준학성분별위93.3%、94.4%화93.8%.원처전이33례,PET-CT균능정학진단.결론 PET-CT현상융합료공능대사화도상해부,대폐원발조화기타장기적전이능작출정학적진단.대NSCLC진단적준학성체90%이상.
Objective To investigate the value of integrated PET-CT with 18F-FDG in the diagnosis of non-small cell lung cancer.Methods 91 patients with non-small-cell lung cancer(NSCLC)and 10patients with benign disease underwent integrated PET-CT from February 2004 to May 2005.Other diagnostic procedures were analysed. Results 91 patients with lung cancer were found by positive SUV and pathologically confirmed.Of the 10 patients with benign disease.positive SUV were found in 3 cases.2 cases with tuberculosis and 1 case with inflammatory pseudotumor were confirmed.Negative SUV were found in 7cases.1 case was incorrectly diagnosed by integrated PET-CT.The sensitivity,specificity and accuracy of integrated PET-CT in the diagnosis of NSCLC were 100%,90%,99%,respectively.Forty-eight of 91patients with lung cancer underwent operation.There were 30 cases with and 18 cases without mediastinal nodal metastases.There were two false negative cases and one false positive case.The sensitivity,specificity and accuracy of integrated PET-CT in the diagnosis mediastinal nodal metastases were 93.3%,94.4%,93.8%.respectively.Metastases were identified in 33 cases.Conclusion Functional metabolism and anatomy imaging are fused in integrated PET-CT.The primary site and metastases lesion are correctly diagnosed by integrated PET-CT.The accuracy of integrated PET-CT in the diagnosis of NSCLC is over 90%.