CAJ | 학술논문

目的:了解大连獐子岛地区2型糖尿病及糖调节受损的患病情况及危险因素,为制定适宜的干预措施提供依据. 方法:2007年采用整群随机抽样的方法对大连獐子岛地区的907例18岁以上常住居民进行横断面调查.采用问卷调查、体格测量、食物摄入频率和回顾性膳食调查;空腹静脉采血测定血尿酸、空腹及餐后2 h血糖、血总胆固醇、血三酰甘油,血清胰岛素等生化及免疫指标. 结果:问卷回收率为95.9%.大连獐子岛地区2型糖尿病及糖调节受损的患病率分别为11.36%,37.38%,男性及女性上述两指标比较差异无显著性意义(P > 0.05),而在糖尿病的患病居民中,仅有29.13%的人知道自己患病.2型糖尿病和糖调节受损的患病率均随年龄的增长而增加(P < 0.01).多因素非条件Logistic回归分析结果显示:年龄、文化程度、饮酒和高胆固醇血症与糖调节受损的发生有关;而年龄、文化程度、高三酰甘油血症、高胆固醇血症、BMI和高血压可增加糖尿病的危险性. 结论:大连獐子岛地区2型糖尿病和糖调节受损的患病率较高,而糖尿病的知晓率低,且与多种因素有关,应采取综合性措施进行防治,以降低患病率.
목적:료해대련장자도지구2형당뇨병급당조절수손적환병정황급위험인소,위제정괄의적간예조시제공의거. 방법:2007년채용정군수궤추양적방법대대련장자도지구적907례18세이상상주거민진행횡단면조사.채용문권조사、체격측량、식물섭입빈솔화회고성선식조사;공복정맥채혈측정혈뇨산、공복급찬후2 h혈당、혈총담고순、혈삼선감유,혈청이도소등생화급면역지표. 결과:문권회수솔위95.9%.대련장자도지구2형당뇨병급당조절수손적환병솔분별위11.36%,37.38%,남성급녀성상술량지표비교차이무현저성의의(P > 0.05),이재당뇨병적환병거민중,부유29.13%적인지도자기환병.2형당뇨병화당조절수손적환병솔균수년령적증장이증가(P < 0.01).다인소비조건Logistic회귀분석결과현시:년령、문화정도、음주화고담고순혈증여당조절수손적발생유관;이년령、문화정도、고삼선감유혈증、고담고순혈증、BMI화고혈압가증가당뇨병적위험성. 결론:대련장자도지구2형당뇨병화당조절수손적환병솔교고,이당뇨병적지효솔저,차여다충인소유관,응채취종합성조시진행방치,이강저환병솔.
OBJECTIVED: To explore the prevalence and risk factors of type 2 diabetes mellitus (T2DM) and impaired glucose regulation (IGR) in Zhangzi Island of Dalian, additionally to provide a better understanding of further intervention. METHODS: A cross-sectional study was performed in 907 residents aged over 18 years from Zhangzi Island of Dalian. The questionnaire, physical measurement, food intake frequency and previously dietary investigation were used in the analysis. Simultaneously, a series of biochemistrical and immune index was measured, including blood uric acid, blood sugar, total cholesterol, triacylglycerol, as well as serum insulin.RESULTS: The recovery rate of questionnaire was 95.9%, which demonstrated that the prevalence rates of T2DM and IGR in Zhangzi Island were 11.36% and 37.38%, there was no significant differences between males and females (P > 0.05). Only 29.13% of the people with T2DM were aware of the condition. The prevalence of DM and IGR were increased significantly with age (P < 0.01). The results of the logistic regression showed that age, education, alcohol drinking and hypercholesteremia were the risk factors of IGR. In addition, age, education, hypercholesteremia, hypertriglyceridemia, body mass index and hypertension were the important risk factors for the development of DM. CONCLUSION: The prevalence rates of T2DM and IGR in Zhangzi Island of Dalian are high with a low awareness. Health promotion on lifestyle changes may help to increase the public awareness and reduce the prevalence.