CAJ | 학술논문

原发性视网膜脱离手术治疗的历史已有90多年.虽然视网膜解剖复位的成功率可以达到90％以上,但视力恢复仍不够令人满意.视网膜脱离复位后究竟发生了什么变化?通过动物疾病模型的研究,已知主要在视网膜色素上皮细胞、光感受器细胞及其界面出现一系列的细胞学反应,其结构和功能重建需要较长时间.近年光学相干断层扫描(OCT)发现,光感受器内节与外节连接(IS/OS连接)断裂、外界膜(ELM)断裂,以及黄斑的微小病变,是视力后果不良的影响因素.关于手术方式等治疗因素对视力恢复的影响,仍有争议.因此,应更多地关注视网膜复位后的视力恢复,进行相关的基础和临床研究.
원발성시망막탈리수술치료적역사이유90다년.수연시망막해부복위적성공솔가이체도90％이상,단시력회복잉불구령인만의.시망막탈리복위후구경발생료십요변화?통과동물질병모형적연구,이지주요재시망막색소상피세포、광감수기세포급기계면출현일계렬적세포학반응,기결구화공능중건수요교장시간.근년광학상간단층소묘(OCT)발현,광감수기내절여외절련접(IS/OS련접)단렬、외계막(ELM)단렬,이급황반적미소병변,시시력후과불량적영향인소.관우수술방식등치료인소대시력회복적영향,잉유쟁의.인차,응경다지관주시망막복위후적시력회복,진행상관적기출화림상연구.
More than 90 years have elapsed in the history of surgical treatment for primary retinal detachment.Although the anatomical reattachment rate can reach more than 90％ after surgery,visual function is still far from satisfactory.What happens after reattachment following retinal detachment? Animal models have shown that a series of cytological changes occur mainly in the retinal pigment epithelium and photoreceptors and their junctures.And a relatively long period of tine is required for the remodeling of structure and function.The rupture of the inner segment and outer segment junctures (IS/OS junctures) of the photoreceptors and the external limiting membrane (ELM) and micro-pathologic changes in the maculae were recently found with optical coherence tomography (OCT) and these were responsible for poor visual outcomes.There is still a debate on the effects of the surgical modality on visual outcomes.Therefore,more attention should be paid to visual recovery after retinal reattachment surgery and basic and clinical research can be carried out to solve the problem.