白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2009年
8期
469-470,472
,共3页
肖亮%王志国%范艳玲%陈波%唐庆华%展昭民%张伯龙%马军
肖亮%王誌國%範豔玲%陳波%唐慶華%展昭民%張伯龍%馬軍
초량%왕지국%범염령%진파%당경화%전소민%장백룡%마군
复方丹参%低分子右旋糖酐%肝静脉闭塞性疾病
複方丹參%低分子右鏇糖酐%肝靜脈閉塞性疾病
복방단삼%저분자우선당항%간정맥폐새성질병
FUFANG DANSHEN%Dextran%Hepatic veno-occlusive disease
目的 观察复方丹参联合低分子右旋糖酐注射液预防造血干细胞移植(HSCT)后肝静脉闭塞病(HVOD)的临床效果.方法 在HSCT预处理时开始用复方丹参注射液20ml,1次/d,静脉滴注,低分子右旋糖酐注射液250 ml,2次/d,静脉滴注,同时用保护肝细胞类药物.当血小板数降至30×109/L时停用复方丹参与低分子右旋糖酐,不再应用.结果 85次HSCT使用复方丹参联合低分子右旋糖酐预防HVOD均无HVOD发生,用复方丹参加低分子右旋糖酐时未发生出血.结论 复方丹参联合低分子右旋糖酐预防HSCT后HVOD安全有效.
目的 觀察複方丹參聯閤低分子右鏇糖酐註射液預防造血榦細胞移植(HSCT)後肝靜脈閉塞病(HVOD)的臨床效果.方法 在HSCT預處理時開始用複方丹參註射液20ml,1次/d,靜脈滴註,低分子右鏇糖酐註射液250 ml,2次/d,靜脈滴註,同時用保護肝細胞類藥物.噹血小闆數降至30×109/L時停用複方丹參與低分子右鏇糖酐,不再應用.結果 85次HSCT使用複方丹參聯閤低分子右鏇糖酐預防HVOD均無HVOD髮生,用複方丹參加低分子右鏇糖酐時未髮生齣血.結論 複方丹參聯閤低分子右鏇糖酐預防HSCT後HVOD安全有效.
목적 관찰복방단삼연합저분자우선당항주사액예방조혈간세포이식(HSCT)후간정맥폐새병(HVOD)적림상효과.방법 재HSCT예처리시개시용복방단삼주사액20ml,1차/d,정맥적주,저분자우선당항주사액250 ml,2차/d,정맥적주,동시용보호간세포류약물.당혈소판수강지30×109/L시정용복방단삼여저분자우선당항,불재응용.결과 85차HSCT사용복방단삼연합저분자우선당항예방HVOD균무HVOD발생,용복방단삼가저분자우선당항시미발생출혈.결론 복방단삼연합저분자우선당항예방HSCT후HVOD안전유효.
Objective To investigate the clinic effect of the Salvia miltiorrhiza combined with dextran to prevent veno-occlusive disease after hematopoietic stem cell transplantation. Methods In the process of the pretreatment of the hematopoietic stem cell transplantation, patients were treated with salvia miltiorrhiza (20 ml/d), dextran(250 ml, twice a day) by venous transfusion and the drugs to protect the liver cell was used in the same time. When the count of platelet dropped to 30×109/L, salvia miltiorrhiza and dextranware stopped applying forever. Results Veno-occlusive disease and hemorrhage has not occurred during 85 times of the hematopoietic stem cell transplantation treated with salvia miltiorrhiza and dextran. Conclusion We conclude that the combined treatment with salvia miltiorrhiza and dextran is safe and effective to prevent veno-occlusive disease after hematopoietic stem cell transplantation.