中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
1期
34-36
,共3页
重症监护室%深部真菌感染%危险因素
重癥鑑護室%深部真菌感染%危險因素
중증감호실%심부진균감염%위험인소
Intensive care unit%Deep fungal infection%Risk factor
目的 探讨我院重症监护室(ICU)患者深部真菌感染的危险因素和病原学资料.方法 采用回顾性调查方法,对我院ICU科2007年1月至2009年12月收治的617例患者逐一调查.结果 ICU患者深部真菌感染的发生率为10.21%,其中白色念珠菌占67.11%;感染部位以下呼吸道最多(占48.68%),其次为泌尿系统(占25%);白色念珠菌对氟康唑、益康唑、酮康唑的耐药率分别为17.39%、17.39%和19.57%;广谱抗生素应用≥4 d、侵入性操作、糖皮质激素使用是ICU患者发生深部真菌感染的独立危险因素.结论 ICU患者发生真菌感染是多种高危因素综合作用的结果.减少或避免盲目使用广谱抗生素等导致深部真菌感染的危险因素,加强全身的综合性治疗,可降低深部真菌感染的发生率.
目的 探討我院重癥鑑護室(ICU)患者深部真菌感染的危險因素和病原學資料.方法 採用迴顧性調查方法,對我院ICU科2007年1月至2009年12月收治的617例患者逐一調查.結果 ICU患者深部真菌感染的髮生率為10.21%,其中白色唸珠菌佔67.11%;感染部位以下呼吸道最多(佔48.68%),其次為泌尿繫統(佔25%);白色唸珠菌對氟康唑、益康唑、酮康唑的耐藥率分彆為17.39%、17.39%和19.57%;廣譜抗生素應用≥4 d、侵入性操作、糖皮質激素使用是ICU患者髮生深部真菌感染的獨立危險因素.結論 ICU患者髮生真菌感染是多種高危因素綜閤作用的結果.減少或避免盲目使用廣譜抗生素等導緻深部真菌感染的危險因素,加彊全身的綜閤性治療,可降低深部真菌感染的髮生率.
목적 탐토아원중증감호실(ICU)환자심부진균감염적위험인소화병원학자료.방법 채용회고성조사방법,대아원ICU과2007년1월지2009년12월수치적617례환자축일조사.결과 ICU환자심부진균감염적발생솔위10.21%,기중백색념주균점67.11%;감염부위이하호흡도최다(점48.68%),기차위비뇨계통(점25%);백색념주균대불강서、익강서、동강서적내약솔분별위17.39%、17.39%화19.57%;엄보항생소응용≥4 d、침입성조작、당피질격소사용시ICU환자발생심부진균감염적독립위험인소.결론 ICU환자발생진균감염시다충고위인소종합작용적결과.감소혹피면맹목사용엄보항생소등도치심부진균감염적위험인소,가강전신적종합성치료,가강저심부진균감염적발생솔.
Objective To explore the risk factors and etiology material of deep fungal infection patients in our intensive care unit (ICU). Methods Six hundred and seventeen patients treated by survey using a retrospective investigation in the ICU room, from Jan. 2007 to Dec. 2009. Results The deep fungus infection rate of ICU patients was 10.21%, candida albicans accounted for 67.11%. The lower respiratory tract infection was the most common site(48.68% ), the second was urinary tract (25%).Candida albicans in fluconazol, merchant, ketone health thiazole resistant was 17.39%, 17.39% and 19.57%, respectively. Broad- spectrum antibiotics used ≥ d, intrusive operations experiment and glucocorticoid were the independent risk factors to get the deep fungal infections occurred in the ICU.Conclusions Patients with fungal infection in the ICU has comprehensive risk factors. To reduce or avoid blindly use broad -spectrum antibiotics which could be the deep fungal infection risk factors,strengthen comprehensive treatment of the body, can reduce the incidence of deep fungal infection.
