CAJ | 학술논문

目的观察复方甘草酸苷(肝保护剂)注射液治疗放射性肝病的疗效.方法对66例发生Ⅰ-Ⅱ级放射性肝病的原发性肝癌患者,随机分为治疗组和对照组,对照组采用甘利欣注射液联合目前通用的综合治疗措施.治疗组在此基础上,应用复方甘草酸苷注射液静脉滴注60-100 mL·d~(-1),疗程为4周;疗程结束后,继续服用复方甘草酸苷片150 mg·d~(-1),至16周.结果各项肝功能指标治疗总有效率,治疗组均优于对照组(P<0.05).结论复方甘草酸苷注射液可有效降低放射性肝病患者的转氨酶、胆红素水平,且用药安全.
목적 관찰복방감초산감(간보호제)주사액치료방사성간병적료효.방법 대66례발생Ⅰ-Ⅱ급방사성간병적원발성간암환자,수궤분위치료조화대조조,대조조채용감리흔주사액연합목전통용적종합치료조시.치료조재차기출상,응용복방감초산감주사액정맥적주60-100 mL·d~(-1),료정위4주;료정결속후,계속복용복방감초산감편150 mg·d~(-1),지16주.결과 각항간공능지표치료총유효솔,치료조균우우대조조(P<0.05).결론 복방감초산감주사액가유효강저방사성간병환자적전안매、담홍소수평,차용약안전.
Objective To evaluate the efficacy of compound glycyrrhizin injection for the treatment of radiation-induced liver disease. Methods Sixty-six patients with the first and the second class of radiation-in-duced liver impairment were randomly divided into the trial group and the control group. Diammonium glycyrrhizinate injection and comprehensive treatment were used in the control group. Compound glycyrrhizin injec-tion and the comprehensive treatment were used in the trial group. Com-pound glycyrrhizin injection was administered intravenously with the dose 60-100 mL· d~(-1) , and the course of treatment was 4 weeks. After that, compound glycyrrhizin tablets were given with the dose 150 mg · d~(-1) for another 12 weeks. Results The treatment efficacy rate of liver-func-tion parameters of the trial group was much higher than that of the control group (P < 0. 05). Conclusion Compound glycyrrhizin injection was ef-fective and safe in the treatment of the radiation-induced liver impair-ment.