国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2010年
2期
125-封3
,共1页
磁性%SiO2%制备%表面修饰%应用
磁性%SiO2%製備%錶麵脩飾%應用
자성%SiO2%제비%표면수식%응용
Magnetic%Silica%Synthesis%Surface modification%Application
磁性SiO2微球是一种新型的功能材料,在生物医学领域有着广泛的应用前景,可用于靶向药物、免疫磁珠、蛋白和核酸分离、固定化酶及天然产物的分离与纯化等方面.综述了磁性SiO2微球的制备、表面修饰及其在生物医学领域的应用发展趋势和前景,重点分析了核壳型和分散型微球所采用的几种制备方法,如溶胶-凝胶法、液相沉积法、自组装法和微乳液法等.
磁性SiO2微毬是一種新型的功能材料,在生物醫學領域有著廣汎的應用前景,可用于靶嚮藥物、免疫磁珠、蛋白和覈痠分離、固定化酶及天然產物的分離與純化等方麵.綜述瞭磁性SiO2微毬的製備、錶麵脩飾及其在生物醫學領域的應用髮展趨勢和前景,重點分析瞭覈殼型和分散型微毬所採用的幾種製備方法,如溶膠-凝膠法、液相沉積法、自組裝法和微乳液法等.
자성SiO2미구시일충신형적공능재료,재생물의학영역유착엄범적응용전경,가용우파향약물、면역자주、단백화핵산분리、고정화매급천연산물적분리여순화등방면.종술료자성SiO2미구적제비、표면수식급기재생물의학영역적응용발전추세화전경,중점분석료핵각형화분산형미구소채용적궤충제비방법,여용효-응효법、액상침적법、자조장법화미유액법등.
Magnetic silica micro-spheres is a kind of novel functional materials, which is expected to be applied to targeted drug delivery, immunomagnetic beads, separation of nucleic acid and protein, immobilization of enzymes and isolation and purification of natural products in biomedicine. This review describes the methods of synthesis, surface modification and applications of magnetic silica micro-spheres, which focus on the various strategies in synthesis with core-shell and mosaic structure, sol-gel method, liquid phase deposition, self-assembly technique and micro-emulsion method. Finally, foregroud and prospect of the research are also discussed.
