CAJ | 학술논문

目的观察犬钛网成形自体颗粒骨移植修复下颌骨节段性缺损并同期植入钛种植体后的骨愈合和骨结合情况.方法 5只Beagle犬,一侧下颌骨制备长40 mm的节段性缺损;钛网成形修复下颌骨缺损.将切除后的下颌骨和自体髂骨剪成直径约2mm颗粒,骨皮质、骨松质体积比3∶1混合,紧密充填在钛网内,将2枚纯钛种植体埋置于颗粒骨内,术后6个月处死动物.用下颌骨X线片、组织学切片、扫描电镜以及能谱分析观察钛网内颗粒骨愈合以及种植体骨结合的情况.结果钛网成形自体颗粒骨移植重建后的下颌骨外形满意,功能正常、颗粒骨成骨良好、结构优良,未见明显骨吸收.同期植入的种植体能够与周围骨组织形成良好的骨结合,并有促进邻近骨组织结构优化的趋势.结论钛网成形自体颗粒骨移植是一种修复下颌骨节段性缺损的好方法,当修复后下颌骨形态良好、骨质优良、骨量充足时可以同期植入种植体.
목적 관찰견태망성형자체과립골이식수복하합골절단성결손병동기식입태충식체후적골유합화골결합정황.방법 5지Beagle견,일측하합골제비장40 mm적절단성결손;태망성형수복하합골결손.장절제후적하합골화자체가골전성직경약2mm과립,골피질、골송질체적비3∶1혼합,긴밀충전재태망내,장2매순태충식체매치우과립골내,술후6개월처사동물.용하합골X선편、조직학절편、소묘전경이급능보분석관찰태망내과립골유합이급충식체골결합적정황.결과 태망성형자체과립골이식중건후적하합골외형만의,공능정상、과립골성골량호、결구우량,미견명현골흡수.동기식입적충식체능구여주위골조직형성량호적골결합,병유촉진린근골조직결구우화적추세.결론 태망성형자체과립골이식시일충수복하합골절단성결손적호방법,당수복후하합골형태량호、골질우량、골량충족시가이동기식입충식체.
Objective To observe the healing and bone formation of the autogenous particulate bone graft and osseointegration of the implants in shaped titanium mesh with autogenous particulate bone graft and simultaneous implant for reconstructing segmental mandibular defect in dogs. Methods Five Beagle dogs were prepared with unilateral 40 mm segmental mandibular defect. Titanium mesh was shaped according to the mandibular defect and was fixed with titanium screws. The ablated mandibular bone and iliac bone were crashed to approximately 2 mm particulates which then filled the titanium mesh graft. The dogs were sacrificed after six months. X-ray films, histological sections, Scanning electron microscopy (SEM) and Energy disperse analysis of the reconstructed mandibles were examined to evaluate the bone formation of the bone graft and osseointegration of the implants. Results The outline of the reconstructed mandible was satisfactory and its function was excellent. The ossific fusion among the particulate bone grafts was fine and no resorption was found. All implants showed excellent osseointegration with the bone graft. The bone near the implant was more compact than the bone away from it. The structure of the bone near implant was optimized because of simultaneous implant in shaped titanium mesh.Conclusions The shaped titanium mesh with autogenous particulate bone graft is a good method for reconstructing segmental mandibular defect, and simultaneous implant is feasible in the reconstructed mandible in dogs.